Supplementary Material for Gilljam et al. (2009)
Search results for the PCNA binding motifs PIP (Warbrick, 2000) and APIM (Gilljam et al., 2009) against orthologous sequences using confind (Drabløs, unpublished). The confind tool identifies pattern hits in a target organism (here human), and filters potential hits against (predicted) protein localisation and motif conservation in orthologous sequences.
Details for each run can be found in output.
Supplementary Material for Olaisen et al. (Submitted)
Search results for the PCNA binding motifs PIP (Warbrick, 2000) and APIM (Gilljam et al, 2009) against orthologous sequences using confind (Drabløs, unpublished), with human and yeast as target organisms, and without any filtering for subcellular localisation. Out of the 503 entries for APIM hits in humans, 125 entries do not have any hit in at least one of the three mammalian species used for filtering (cow, rat and mouse), leaving 378 well-conserved hits in the mammals.
Details for each run can be found in the output.
Bioinformatics & Gene Regulation
Department of Cancer Research and Molecular Medicine
Norwegian University of Science and Technology