confind

confind (c) Finn Drablos, NTNU 2007,2012
Version 02.10.2012
Program started Fri Dec 21 13:49:03 CET 2012
----------
Configuration file for APIM motif

Version FD 02-10-2012

Datasets are from Inparanoid 7.0. Gene descriptions are
taken from Inparanoid 7.0. Localisation data are from eSLDB.

Using K as equivalence for KR in consensus
Using F as equivalence for FYW in consensus
Using L as equivalence for LVI in consensus
----------
Found 5884 sequences in ./lib/S.cerevisiae.fa
Got match in 280 sequences against pattern [KR][FYW](([LVI][ALVI])|([ALVI][LVI]))[KR]
Removed 0 entries with no info in ./ref/eSLDB_Saccharomyces_cerevisiae_TS.txt matching .*
There are 280 entries left
Found 195 orthologs in Kl (Kluyveromyces lactis)
Found 183 orthologs in Ca (Candida albicans)
Found 168 orthologs in Yl (Yarrowia lipolytica)
Found 155 orthologs in Af (Aspergillus fumigatus)
Found 140 orthologs in Nc (Neurospora crassa)
Found 143 orthologs in Sp (Schizosaccharomyces pombe)
Found 123 orthologs in Cn (Cryptococcus neoformans)
Found 114 orthologs in Ro (Rhizopus oryzae)
Removed 60 entries without orthologs
There are 220 entries left
Created 69 new sequence files
Added 355 new orthologs to these sequence files
Ran ClustalW on 69 library files
Removed 136 sequences where pattern was not conserved
There are 84 entries left
Missing information on gene for 0 proteins
Removed 0 duplicate sequences representing the same gene
There are 84 entries left
Description is missing for 0 genes
----------
Pro - Protein number (green if on priority list)
# - Motif number i protein
CI - Entry is accepted according to Consensus or Individual pattern hits
Protein ID / Gene ID - IDs from input data
Pos - Position of motif in sequence
Alignment - Alignment of motif (UPPER case) and flanking region (lower case)
   lower case only - no hit by motif, "-----" - gaps, "....." - missing protein
Ortho ID - ID of Orthologs, with organism code (see above)
Description
Pro # CI Protein ID
Gene ID
Pos Alignment Ortho ID Description
1 1 CI YDR051C
YDR051C
315
302
218
206
-
-
-
-
-
mvmeldesinRYVLRtvlpkwtdce
ivmeldekddRYVLRttlpkwc---
lvmkkddetqkyhlktrlltwddve
iimkrpehthkfellnkmetwhele
.........................
.........................
.........................
.........................
.........................
Sc_YDR051C
Kl_KLLA0F18810g
Ca_CAL0004865
Yl_YALI0F11781g
Af
Nc
Sp
Cn
Ro
Protein of unknown function; interacts with Hsp82p in two-hybrid assay; deletion confers sensitivity to Nickel
2 1 CI YML127W
RSC9
466
451
496
495
471
-
599
-
458
gk-------kRFVIKgiqprfkalg
sk-------kKFVIRgiqprrkals
pgeenqapkkKFIIKgiqprqfpvs
gt-------kKFIIKgiqprkepvd
at--------KFIIKgirpletayt
.........................
pv--------eyvingikrrkfpts
.........................
en-----------------------
Sc_YML127W
Kl_KLLA0D10461g
Ca_CAL0001606
Yl_YALI0F29997g
Af_AFUA_6G07810.t1
Nc
Sp_SPBC1703.02
Cn
Ro_RO3T_09289
Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
3 1 CI YBR118W
TEF2
421
421
421
422
456
422
421
421
421
eafseypplgRFAVRdmrqtvavgv
eafsdypplgRFAVRdmrqtvavgv
eaftdypplgRFAVRdmrqtvavgv
eafteypplgRFAVRdmrqtvavgv
esftdypplgRFAVRdmrqtvavgv
eaftdypplgRFAVRdmrqtvavgv
eaftdyaplgRFAVRdmrqtvavgv
etyadypplgRFAVRdmrqtvavgv
eaytdypplgRFAVRdmrqtvavgv
Sc_YBR118W
Kl_KLLA0B08998g
Ca_CAL0004558
Yl_YALI0C09141g
Af_AFUA_1G06390.t1
Nc_NCUT_01155
Sp_SPBC839.15c
Cn_cn13119
Ro_RO3T_10089
Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes
4 1 CI YPR166C
MRP2
42
42
42
38
40
40
32
28
26
keneilvkslKFIARnmnlptklrl
adnevtvkalKFIARnttlpprsrm
aehevtrnalKYIARneelpararv
aqqeinrralksisqnttlpmkqri
eqyeperqalRYIIRnttlpqrvra
leaeperqalRYVIRnttlpartra
aeheverqsnlyiyrnpelplrvrl
eqmevqrraflyvarnttlpatvrh
adneivrqafkyitrnetmparvrh
Sc_YPR166C
Kl_KLLA0B10648g
Ca_CAL0004723
Yl_YALI0D21626g
Af_AFUA_2G02270.t1
Nc_NCUT_00569
Sp_SPAC23H3.07c
Cn_cn02283
Ro_RO3T_05687
Mitochondrial ribosomal protein of the small subunit
5 1 CI YOR112W
CEX1
426
419
449
451
433
406
422
468
359
terqlnnellRFLAKtqvdsdveir
terqlnndllrvlaktqvdkdigir
svkqvnqellrilaksqmdpkpsir
nsriknndllRYLAKthndkepgir
sdrtingellKFLARtandeqpgir
sdrtingdllRYLAKtandeqpgir
skktlnnellrslavvqndqhptlr
sdrilnndllrvlakmqmdtepsir
neriinydllKYLAKlqmdpepgir
Sc_YOR112W
Kl_KLLA0F23694g
Ca_CAL0001199
Yl_YALI0E27698g
Af_AFUA_1G09620.t1
Nc_NCUT_03812
Sp_SPAC15A10.13
Cn_cn08320
Ro_RO3T_01512
Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p
6 1 C YHR099W
TRA1
1939
1953
1929
1961
1891
1880
1884
1802
1761
allrsshveaRYLVKqsldvltpvl
ailrvhqiearfmvkesldllapvv
allrthqtdsRYLVKqaldilapvm
allktsqnearqlvkqaldllapvl
allrahqnegkalvtqaldvlapvl
sllktnqnegrtlvtqalelmapvm
silktyqpevrafiefslasllsvl
gvlrlkdtdnrvlyrqaidtlassl
allrahssearvlvkqgldiiapvl
Sc_YHR099W
Kl_KLLA0F22066g
Ca_CAL0003086
Yl_YALI0C02057g
Af_AFUA_5G02570.t1
Nc_NCUT_04286
Sp_SPBP16F5.03c
Cn_cn01601
Ro_RO3T_02880
Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation
6 2 C YHR099W
TRA1
2624
2616
2649
2668
2647
2638
2548
2465
2528
s-lelpphlvkylaisynawyqsin
s-lelpphlvrylgitfnawyqsid
d-lqlppfaveclasnfdawsqgih
g-llmpphllkylgksfdgwfeavk
prfkvpphvmkylsrtydawytaas
pecrlpphvlkfeaktfdawytalc
aklelpphlvkylgklygvyhesvs
vpitlpptlvRFLAKnfnawyvgfe
pvvqlpahlvkylgkthncwhiaie
Sc_YHR099W
Kl_KLLA0F22066g
Ca_CAL0003086
Yl_YALI0C02057g
Af_AFUA_5G02570.t1
Nc_NCUT_04286
Sp_SPBP16F5.03c
Cn_cn01601
Ro_RO3T_02880
Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation
7 1 C YPR119W
CLB2
346
392
323
380
347
358
321
353
346
ctedeikegeKFILKtlkfnlnypn
cdeeeikegeKFILKtlefnlnypn
ytpeevvqaekymltilnfdlnypn
ypedeilraerfilqvlqfnlsypn
ftdkeildaerhilatleynmsypn
fteaeilsaerfilstlnydlsypn
ydeeeilqaeRYILRvlefnlaypn
ytveellkaerymlstlqfdmsypn
idedelvraecfilqvldfrlcyan
Sc_YPR119W
Kl_KLLA0D15543g
Ca_CAL0004596
Yl_YALI0B15180g
Af_AFUA_4G12160.t1
Nc_NCUT_01937
Sp_SPBC582.03
Cn_cn10336
Ro_RO3T_03479
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
8 1 C YHL029C
YHL029C
188
148
248
288
-
-
-
-
-
iietlknaivKFLLKwskifkyesg
----lkecvwqflrkwnkickyesg
---ilenaimkftlkwgkiikydss
rfdiyedaiesfltky--hvkyesg
.........................
.........................
.........................
.........................
.........................
Sc_YHL029C
Kl_KLLA0D03861g
Ca_CAL0004930
Yl_YALI0C00473g
Af
Nc
Sp
Cn
Ro
Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
9 1 C YGL131C
SNT2
249
266
298
192
353
449
213
0
128
nifyfdelfdrytlkyykvystdki
ncfyfnqlfdrytlkyyqmektdqm
nqfyfdklfdrymikfydvlstanl
nhfyftqfydRYILRfyeivpthtm
dsfwydkmfdryihryyevvptkkv
dcfwfeklydryiqknyeviptkqi
ksyyfdrlfdqninkvfdvvpvtqv
-------------------------
dhfyynqlydryiqrvydvvpcetv
Sc_YGL131C
Kl_KLLA0B02178g
Ca_CAL0002960
Yl_YALI0E30547g
Af_AFUA_1G05240.t1
Nc_NCUT_07306
Sp_SPAC3H1.12c
Cn_cn04066
Ro_RO3T_01596
DNA binding protein with similarity to the S. pombe Snt2 protein
10 1 C YHR137W
ARO9
385
402
397
403
-
-
-
-
-
mkeamfegwirwimqiaskynhrkn
fngdkvrawlswvmkvageythrrn
-----vdgwlewilkmrlnysyrkd
--------wlrwclllrnqylerrn
.........................
.........................
.........................
.........................
.........................
Sc_YHR137W
Kl_KLLA0D11110g
Ca_CAL0002883
Yl_YALI0C05258g
Af
Nc
Sp
Cn
Ro
Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism
11 1 CI YPL137C
GIP3
947
908
1020
-
884
-
-
-
-
stkvkkdttkRYLLKkyiekfhilh
saklqedstkRYLLKrywekihtih
kgkkedikmqriisdsvlertrsir
.........................
gddicededepapdedyviggtgvv
.........................
.........................
.........................
.........................
Sc_YPL137C
Kl_KLLA0D07216g
Ca_CAL0003186
Yl
Af_AFUA_1G12900.t1
Nc
Sp
Cn
Ro
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
12 1 CI YOR259C
RPT4
116
113
107
89
72
69
67
84
75
gevmkelseeKYIVKassgpryivg
gevmkelseeKYIVKassgpryivg
gevlkqlddeRYIVKtssgpryivg
gevlkqldeeRFIVKasngpryivg
gevlkqldeeRFIVKassgpryvvg
gevlkqlddeRFIVKassgpryvvg
gevlkqldseRFIVKassgpryvvg
gevlkqlddeRFIVKassgpryvvs
gevlkqlddeRFIVKntsgpryvvg
Sc_YOR259C
Kl_KLLA0C09592g
Ca_CAL0005827
Yl_YALI0E21868g
Af_AFUA_6G06780.t1
Nc_NCUT_07349
Sp_SPCC1682.16
Cn_cn10016
Ro_RO3T_05069
One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle
13 1 C YER077C
YER077C
631
663
900
-
-
-
-
-
-
kgte----rkKFLARrhllrlkqil
aedsnsllkrkflfrrhlirlrkri
tntsvvvstypklmeqeifryifvk
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YER077C
Kl_KLLA0C07689g
Ca_CAL0000929
Yl
Af
Nc
Sp
Cn
Ro
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
14 1 C YDR457W
TOM1
383
387
407
381
484
513
367
396
78
ishgllfqilRYIAKtlrea-----
mshgllfqilkyisklitenn----
vshgilfqclrhiwkmvkdqk----
vshgllmhiirtlisdlkerr----
vnhgvlmfltrkavnelasde--rd
vnhgillyviriavaemkedapvdd
vsyglmmnlvrdfsknlenpn----
vnhgvlvtffrhlndrlvagea---
anhgiimqilrkvntneeysqs---
Sc_YDR457W
Kl_KLLA0B01804g
Ca_CAL0001517
Yl_YALI0B05940g
Af_AFUA_4G10780.t1
Nc_NCUT_08465
Sp_SPAC19D5.04
Cn_cn08122
Ro_RO3T_06596
E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators
14 2 C YDR457W
TOM1
517
521
542
511
628
658
504
528
200
relayirsllklvlkllstd-----
rqiafirsllklvlkllscd-----
rqanyirnlmklvadliqsd-----
yragwlktilkfvlqvmptg-----
fqqqtlrwmfrfvnhimqhn----g
yhqqtlkwllKFIHHvmantysfdg
dryfllknllkfvlhliqsg-----
cannplktilrsiqrlmqas-----
drlsaikamlRFLLRmmess-----
Sc_YDR457W
Kl_KLLA0B01804g
Ca_CAL0001517
Yl_YALI0B05940g
Af_AFUA_4G10780.t1
Nc_NCUT_08465
Sp_SPAC19D5.04
Cn_cn08122
Ro_RO3T_06596
E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators
15 1 C YCR033W
SNT1
484
525
473
867
-
-
79
720
452
qkrnkiiseqKYLLKkairnfseyp
kpreervknqkylltkpieylfdyp
khhesganylkyslarpivdfnefp
lprservaemrylrsiplkstrdyk
.........................
.........................
lqekylqniyaltqnqlfknvedys
geeqdelgaekarelnliasvkaaq
eenmddwseeekwskplynsieeyt
Sc_YCR033W
Kl_KLLA0C03564g
Ca_CAL0003554
Yl_YALI0B20262g
Af
Nc
Sp_SPAC22E12.19
Cn_cn01044
Ro_RO3T_09691
Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein
16 1 C YOL049W
GSH2
166
165
157
166
174
170
166
167
89
glsekvdrlhsylnra-nkydpkg-
glstkvgelhdylnks-gnysdng-
glsskigqlhqylngt-gqydskyn
gltskvadlhrylaat-gaygdda-
glsslvrklhselltsppgypisyp
glstqtsllhkhlaqh--eypllss
gvskavsnlhaycsqs-glyrkpl-
alsqragelhKYLAKasrnyydis-
slsvrtselhrfllstlkgyggnq-
Sc_YOL049W
Kl_KLLA0F07557g
Ca_CAL0002106
Yl_YALI0C17831g
Af_AFUA_5G06610.t1
Nc_NCUT_06031
Sp_SPAC3F10.04
Cn_cn10268
Ro_RO3T_00729
Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock
16 2 C YOL049W
GSH2
378
374
371
376
400
400
383
393
252
rlal--sepsKYVLKpqregggnnv
klal--tepenyvlkpqregggnni
klaf--eepeKFVLKpqregggnnv
qlar--tepeRFVLKpqregggnni
elalnpetavnhvlkpqregggnnv
slatsptqcqkyvmkpqregggnnf
klaf--ekpedfvlkpqregggnnt
klar--qepeRFVLKpqregggnni
emal--ekpdelvmkpqreggghni
Sc_YOL049W
Kl_KLLA0F07557g
Ca_CAL0002106
Yl_YALI0C17831g
Af_AFUA_5G06610.t1
Nc_NCUT_06031
Sp_SPAC3F10.04
Cn_cn10268
Ro_RO3T_00729
Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock
17 1 CI YJL107C
YJL107C
345
-
-
758
-
-
-
-
-
vhiadilqrhRFILRmcralmmyga
.........................
.........................
vhiaellqrqRFILRmcralmlyga
.........................
.........................
.........................
.........................
.........................
Sc_YJL107C
Kl
Ca
Yl_YALI0E24651g
Af
Nc
Sp
Cn
Ro
Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
18 1 C YNR019W
ARE2
546
499
513
447
482
478
441
511
-
fsriwnipvhKFLLRhvyhssmssf
fsrlwnrpvhsfllrhvyhssisay
fanqwnrcvhKFLLRhvyhssisaf
fsrewnipvyqflkrhvyhssisaf
fsrewnipvhhflrrhvyfpslsyf
fardwnrpvhnfllrhvyhssisam
fsrewnkpvhvflmrhvyhssisgf
farkwnkpvhtfllrhvyastmttl
.........................
Sc_YNR019W
Kl_KLLA0C09152g
Ca_CAL0006272
Yl_YALI0F06578g
Af_AFUA_1G06040.t1
Nc_NCUT_03654
Sp_SPAC13G7.05
Cn_cn06362
Ro
Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen
19 1 CI YGL163C
RAD54
549
544
496
454
454
461
504
473
446
qlqklstivsKFIIRrtndilakyl
rlrqlsnivsKFIIRrtnnilakyl
klnelsqmvsKFIIRrtndilskyl
kllemasivspliirrtndilskyl
rlaelsgivnKFIIRrtndilskyl
clvellaivnKFIIRrtndilskyl
klaelakivnRFIIRrtndilskyl
klkelgglvsKFIIRrtndllskyl
kvaefwkivsrftirrtndilskyl
Sc_YGL163C
Kl_KLLA0A03069g
Ca_CAL0001568
Yl_YALI0B07513g
Af_AFUA_6G12910.t1
Nc_NCUT_03186
Sp_SPAC15A10.03c
Cn_cn04353
Ro_RO3T_02508
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
20 1 CI YGL084C
GUP1
416
443
437
423
466
462
437
432
254
fwrawhrsynKWVVRyiyiplggsk
fwrawhrsynKWVIRyiyiplggsg
fwrawhrsynRWVIRyiyipmggsg
fwrawhrsfnRWIIRyvygpiggss
fwrgwhrsfnRWIVRylyiplggga
fwrswhrsfyrwtlryiyiplgg--
fwrawhrsfnRWLIRyiyvplggsn
fwrswhrsfnlwvvryiyvpvggsk
----------------------gtk
Sc_YGL084C
Kl_KLLA0E19185g
Ca_CAL0000013
Yl_YALI0E30283g
Af_AFUA_2G05040.t1
Nc_NCUT_02107
Sp_SPAC24H6.01c
Cn_cn06354
Ro_RO3T_14327
Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; proposed to be involved in glycerol transport
21 1 C YOR255W
OSW1
111
107
-
-
-
-
-
-
-
nlsrlklskrKYALRfyhneifgnn
ghlrswisgrkfsmkrivnnas---
.........................
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YOR255W
Kl_KLLA0C09779g
Ca
Yl
Af
Nc
Sp
Cn
Ro
Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p
22 1 C YOR176W
HEM15
81
77
71
70
99
92
74
90
80
isakyqktiaKYIAKfrtpkiekqy
isakyqpiiaKYIARfrtpkiekqy
fg-rfqnilaKFIAKrrtpkieehy
lg-pfqgplakfiawrrtpviekhy
lg-rlqsylgpliakrrtpkiqrqy
lg-rlqnylgpliskrrtpkiqkqy
lgy-fqnslgKFIAKrrtpkvqnhy
lp--fqpllapliakrrtpsieeqy
fp--mqsmaakfiatrrtpqikeqy
Sc_YOR176W
Kl_KLLA0F20141g
Ca_CAL0001790
Yl_YALI0F19470g
Af_AFUA_5G07750.t1
Nc_NCUT_08421
Sp_SPCC320.09
Cn_cn06304
Ro_RO3T_05836
Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway
23 1 C YAL026C
DRS2
668
672
676
655
718
720
626
697
542
lvqggadlgyKFIIRkgnsvtvll-
lvqgaadlgfrfdirrpnsvsist-
lvqgaadlgykftirrpkgvtien-
lvdgaatlgyafamrkpktigvdvk
lvegaaalgyrftnrrprsvlfttn
lvdgavqmgyRFVARkpraviiean
lvkgaasigyKFLARkphlvtvsif
lvagaemlgyrfqtrkpksvfidvn
lvkgasmlnykfhtrkpnsiactqr
Sc_YAL026C
Kl_KLLA0A04015g
Ca_CAL0004962
Yl_YALI0E34551g
Af_AFUA_2G08850.t1
Nc_NCUT_00357
Sp_SPBC887.12
Cn_cn01358
Ro_RO3T_04221
Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease
24 1 C YJL109C
UTP10
1534
1539
1583
1419
1551
1555
1420
1783
1869
ieasvheisnsyvlkmndkvfrplf
ieasvhqianvyvlklndkvfrplf
lessfhgcaiafvmklndksfrplf
vqnlfikcliaivlklndktfrplf
tedalndvtikmiyklndttfrpif
iellinetslkmiyklndaafrpmf
vetqavnvflkfvmklsdttfrplf
veesaigsflelvtklneptfkplf
vegsvitafldlvmklnetlfkplf
Sc_YJL109C
Kl_KLLA0F21208g
Ca_CAL0003770
Yl_YALI0E29506g
Af_AFUA_6G13370.t1
Nc_NCUT_00342
Sp_SPBC23E6.04c
Cn_cn08172
Ro_RO3T_09841
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
24 2 C YJL109C
UTP10
1664
1669
1712
1537
1685
1686
1545
1919
2008
-------sigKYLVKaigalasnns
-------vigKYLVKaigslatnns
-------sigKYLVKsvstfvtdvs
----vapenskllikavvalcelas
s---taatviaeavpaitelavaad
-----adnctndlvlavvelaaaad
-------lddkvlvkaivelasvas
p----spqsprpissclanlagstt
tsadylarmntyivpcigqmavtvs
Sc_YJL109C
Kl_KLLA0F21208g
Ca_CAL0003770
Yl_YALI0E29506g
Af_AFUA_6G13370.t1
Nc_NCUT_00342
Sp_SPBC23E6.04c
Cn_cn08172
Ro_RO3T_09841
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
25 1 C YBR203W
COS111
534
381
387
408
-
-
-
-
-
pfsthhpyanKFLLKyapykdlplg
--rshlpftnkfflkyahlrdlplg
----shplinkfllhystskdlpig
-fstahpisspflrqystskdvpvg
.........................
.........................
.........................
.........................
.........................
Sc_YBR203W
Kl_KLLA0E23079g
Ca_CAL0005497
Yl_YALI0B01166g
Af
Nc
Sp
Cn
Ro
Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
26 1 C YBR073W
RDH54
534
540
431
555
518
-
-
546
-
rskemieitkRFILRrtnailekyl
rsdqlieitkRFILRrtneilqqyl
isqqlieltqsfilrrtqailanyl
qsarlssitgqfilrrtadilsrfl
rneelreltskfmlrrtvdilakyl
.........................
.........................
randlaklskefvlrrtaavlenyl
.........................
Sc_YBR073W
Kl_KLLA0F11814g
Ca_CAL0004359
Yl_YALI0E24431g
Af_AFUA_1G15120.t1
Nc
Sp
Cn_cn03333
Ro
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference
27 1 CI YDR489W
SLD5
137
133
102
130
100
89
83
-
-
lcmetelerlKFVIRsyircrlski
lcmeaelerlKFLVRsfircrlski
miietdlerlnyivrlyirtrlskl
liveteleriKYLIRsylrvrllki
silqtdlsrtqflirsflrqrlakl
iviqtelerfKYLVRsflrtriaki
vlmqtelervKFVLRsymrtrinki
.........................
.........................
Sc_YDR489W
Kl_KLLA0F11121g
Ca_CAL0000861
Yl_YALI0B17820g
Af_AFUA_6G08210.t1
Nc_NCUT_09082
Sp_SPBP4H10.21c
Cn
Ro
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
28 1 C YOL008W
COQ10
45
46
26
34
79
-
14
86
-
----htireqRYVLRkainappstv
----sskdeqhyvlkrnirgtpnev
-------kpqsyeiskilhgspkqv
--------pttfsvtqrfnyppgli
----dnnksrvltatrtlpyqpsal
.........................
-------------asrlmpykpsfl
qgvevdgevqryharkilpysqaql
.........................
Sc_YOL008W
Kl_KLLA0C06050g
Ca_CAL0004083
Yl_YALI0A02563g
Af_AFUA_6G07220.t1
Nc
Sp_SPCC16A11.07
Cn_cn05160
Ro
Coenzyme Q (ubiquinone) binding protein, functions in the delivery of Q<sub>6</sub> to its proper location for electron transport during respiration; START domain protein with homologs in bacteria and eukaryotes
29 1 C YDR125C
ECM18
244
206
259
-
-
-
-
-
-
ghsfggylsfKYAVKypnsvnklcl
ghsyggyltfkyslkypdnvhklcl
ghsfggywcgsyalkypenvnnlvl
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YDR125C
Kl_KLLA0F19624g
Ca_CAL0000311
Yl
Af
Nc
Sp
Cn
Ro
Protein of unknown function, similar to Rlp24p
30 1 C YFL049W
SWP82
40
26
-
0
-
-
-
-
-
vpkilirehervilkqilqildqde
vpeyviknhelfilkttlsilnnpe
.........................
-------------------------
.........................
.........................
.........................
.........................
.........................
Sc_YFL049W
Kl_KLLA0D05885g
Ca
Yl_YALI0E06369g
Af
Nc
Sp
Cn
Ro
Member of the SWI/SNF chromatin remodeling complex in which it plays an as yet unidentified role; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p
31 1 C YPR018W
RLF2
583
562
559
500
628
669
531
797
-
rssgkgdlprKWVIKdaqnwenlra
kst-kgd--rrwevkdmnnwehlks
ydk-kss---kweikaemkekycs-
rqgpksd--kRWVLKdi--------
rvg-qrevdkkwvcn----------
vfaskhpdmvraqikasfesmtekq
rkgksvs--dgwiikenfasllss-
regrskdsvwrvyreawiaaglepa
.........................
Sc_YPR018W
Kl_KLLA0D02090g
Ca_CAL0004223
Yl_YALI0F21637g
Af_AFUA_5G03720.t1
Nc_NCUT_03891
Sp_SPBC29A10.03c
Cn_cn03648
Ro
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin
32 1 C YPR031W
NTO1
605
580
601
637
827
824
529
-
602
kvfdivkspqKYLLKinvldifiks
iindiafhpiRYILKdvvwnnltkt
dvvdsvyfplkqlieltimrlnnkf
elirtlllpvtalclrlcdemteqd
sivdtvyfpifpllwpiyekaqgld
dfvdscyfpvyemlipalqkaiqsd
kflnlnyfpaqrllqdtlvkiidld
.........................
ayldlilfpldyiigpvldqise--
Sc_YPR031W
Kl_KLLA0E06491g
Ca_CAL0003263
Yl_YALI0D25674g
Af_AFUA_7G05250.t1
Nc_NCUT_00042
Sp_SPBC17D11.04c
Cn
Ro_RO3T_03265
Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3
33 1 C YLL040C
VPS13
2321
2291
2266
2392
2359
2401
2262
2348
2300
llskvieiapryiisntldipievc
rftkiveispryifrnstsevieim
nltkvisitpryifvnkleeelqiv
kltrfieltprfiihnclkeelrir
kmtkvvtispRFILKnklseeilvr
kmvktvtlapryviqnrlgedinir
sktnivtitsRFIVRnktrwslvia
kltkvitiapRFLVKniysrpikir
klnklitltprfvlsnqmdqniryr
Sc_YLL040C
Kl_KLLA0E00705g
Ca_CAL0001755
Yl_YALI0F06791g
Af_AFUA_4G11560.t1
Nc_NCUT_05723
Sp_SPBC21C3.01c
Cn_cn03502
Ro_RO3T_13642
Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention
34 1 C YLR045C
STU2
479
460
448
426
427
405
425
438
-
ktpqirmectqlfnasmk---eekd
kvpqvkivcskflfellsnwtptet
ktpqnkiasanfvkrcls------t
ktpqvrieslnfilrlls------t
knpqvkqetlKFLIRclr------t
knpqvkegtmKFLVRclr------t
knpqiksscfslfsrsfs------n
knpqvkegtlkflhrslq------t
.........................
Sc_YLR045C
Kl_KLLA0E16325g
Ca_CAL0003948
Yl_YALI0E28371g
Af_AFUA_6G12980.t1
Nc_NCUT_05461
Sp_SPCC895.07
Cn_cn07265
Ro
Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p
35 1 C YOR126C
IAH1
57
59
63
53
65
53
82
51
35
lqrgfkgytsRWALKilpeilkhes
vqrgfsgynsRWALKllpkileqeq
inrgfsgynseharqilpkileset
lvrgysgyntdqavqffhhilehek
inrgfggystahavkvfpkffpkpe
vnrglsgyntsnalkllpqifsppg
dvwgfsgytsrhvlrylpeipleid
inrgfggynsewaipvfeqvfatkk
vnrgfsgfntdwampilkqllptte
Sc_YOR126C
Kl_KLLA0E02509g
Ca_CAL0000954
Yl_YALI0B07227g
Af_AFUA_2G08920.t1
Nc_NCUT_00404
Sp_SPCC126.10
Cn_cn12157
Ro_RO3T_08748
Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing
36 1 CI YNL080C
EOS1
160
147
-
114
-
-
85
-
-
syaildslmvRWIVKystvaailrm
sysildslmvRWIIKyatmaaifrm
.........................
ayavldglmirwivtystpaaivrm
.........................
.........................
sfvlangfllkwlihysigptiirl
.........................
.........................
Sc_YNL080C
Kl_KLLA0E17909g
Ca
Yl_YALI0D01936g
Af
Nc
Sp_SPAPB17E12.08
Cn
Ro
Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene
37 1 CI YBR235W
YBR235W
525
513
-
533
580
466
539
-
-
sqsliyhqvrKYLLRlr--qdniky
sqsliyhqvrKYLLRlr--qdnvky
.........................
sqallyhqvrKYLLRlr--qdhvkf
sqsliyhqvrKYLLRlr--qehvkf
sqnliyhqvrKYLLRlk--pehikf
sqgiiyhqlrkyllqtnkarenikf
.........................
.........................
Sc_YBR235W
Kl_KLLA0F10549g
Ca
Yl_YALI0B04378g
Af_AFUA_4G07770.t1
Nc_NCUT_03469
Sp_SPBC18H10.16
Cn
Ro
Putative ion transporter, similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family; YBR235W is not an essential gene
38 1 CI YGL099W
LSG1
485
494
504
554
505
485
449
548
465
ygsadeprasRYILKdyvngkllyv
fgaadesrasRYILKdyvngkllyi
fgsadepraaRYILKdyvngkllyv
qgnpdesraaRYVLKdyvngkllyc
qgqpdesraaRYVLKdyvngkllfc
lgqpdqsravRYILKdyvngkllyc
hgtpddsraarillkdyvngkllyv
fgmpdtsraaRYVLKdyvnakllfa
qgnpdearaaRYILKdyvngkllfc
Sc_YGL099W
Kl_KLLA0F06666g
Ca_CAL0005034
Yl_YALI0C21956g
Af_AFUA_5G06510.t1
Nc_NCUT_03922
Sp_SPAC3F10.16c
Cn_cn03586
Ro_RO3T_09763
Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm
39 1 CI YKL112W
ABF1
428
254
-
-
-
-
-
-
-
iarrittykaRFVLKkkkmgeyndl
iarrvttykaRFVLKrkkdgvy---
.........................
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YKL112W
Kl_KLLA0F02970g
Ca
Yl
Af
Nc
Sp
Cn
Ro
DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair
40 1 CI YDL191W
RPL35A
115
115
115
118
181
119
117
122
115
rkkqiafpqrKYAIKa---------
rkkqiafpqrKYAIKa---------
rkqriafpqrKFAIKa---------
tkkqthfpqrRYALKa---------
rkkeihfpqrKYAVKtnvvsgseme
kkrtthfplrKFAVKaa--------
ikkeryfplrKYALKa---------
hkknihfpkrkialka---------
qkkeahfplrKYAVKa---------
Sc_YDL191W
Kl_KLLA0F05247g
Ca_CAF0007060
Yl_YALI0A09922g
Af_AFUA_1G10510.t1
Nc_NCUT_01988
Sp_SPCC613.05c
Cn_cn01742
Ro_RO3T_11228
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein
41 1 CI YKL103C
LAP4
261
268
259
235
262
269
-
-
-
lfgkhcihllRYVAKlagve-vsel
lygkhsihllRYIAKllsvk-vsai
lygkhplkllRYIAKlanvs-vgdi
lvgkhsidllrtlskhsgva-vkdm
faatqperlvkiiskelgitdydti
fvstqppklvkliasqlkledytni
.........................
.........................
.........................
Sc_YKL103C
Kl_KLLA0F13574g
Ca_CAL0006379
Yl_YALI0C10494g
Af_AFUA_5G03990.t1
Nc_NCUT_03897
Sp
Cn
Ro
Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway
42 1 C YKL176C
LST4
199
146
242
-
-
-
-
-
-
----------qyn-riaislcipri
----------kstlriaisccvtdd
dtsknnnvnsrfaigivipleslgs
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YKL176C
Kl_KLLA0A06622g
Ca_CAL0002848
Yl
Af
Nc
Sp
Cn
Ro
Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
42 2 C YKL176C
LST4
237
185
281
-
-
-
-
-
-
wltqtqkmligfltknrimqentgn
fldqcentllKYLAKn---------
ytinlqkliykkllvhlnqgltyds
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YKL176C
Kl_KLLA0A06622g
Ca_CAL0002848
Yl
Af
Nc
Sp
Cn
Ro
Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
43 1 C YDL169C
UGX2
219
180
-
-
-
-
-
-
-
dsdtpennhlKWLIK----------
esetlenkllkslvrs---------
.........................
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YDL169C
Kl_KLLA0E19493g
Ca
Yl
Af
Nc
Sp
Cn
Ro
Protein of unknown function, transcript accumulates in response to any combination of stress conditions
44 1 C YJL090C
DPB11
57
57
57
53
78
-
58
-
-
vgsttntnkfKFAVKhrfdiifidi
vg-elftakynfavknrtdivfvsp
vg-drdtekyrfcikyrpdiifida
vg-nqdsekylfashqrldmtflhp
vg-eintakyKFVARersdvvvlkp
.........................
ag-dfdtpkykfaaksrpdikimss
.........................
.........................
Sc_YJL090C
Kl_KLLA0F14300g
Ca_CAL0004555
Yl_YALI0E21978g
Af_AFUA_5G13380.t1
Nc
Sp_SPAC23C4.18c
Cn
Ro
Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis, also required for S/M checkpoint control
45 1 C YPR105C
COG4
390
347
402
324
457
482
353
452
155
qilqnwsmysrfysvkwnefsdlhp
nflqnwsmycqffsmkwlqftngsv
sifenwtlycrfitvkylqepkhrq
milnrwalyrkflagfegg------
vmlsrwslycrfiaetcnvryltas
imlsrwsayshllaqkc--------
aivskwniskifisrlvlrlsqsdg
alggrwalfrrfiwsriadededes
elmnsylvideyllkks--------
Sc_YPR105C
Kl_KLLA0F08184g
Ca_CAL0005896
Yl_YALI0D03113g
Af_AFUA_2G05890.t1
Nc_NCUT_02785
Sp_SPCC338.13
Cn_cn13146
Ro_RO3T_08984
Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
46 1 CI YGL137W
SEC27
62
62
62
62
62
62
63
64
64
qvtetpvragKFIARknwiivgsdd
plcdapvragRFIARknwvvvgsdd
qvtelpvragKFIARknwivvgsdd
evadvplragRFIARknwiivgsdd
eltdvpvragRFIARknwivcgsdd
eltdvpvragRFIARknwiicgsdd
dindvpiracafiarknwfvcgsdd
evtdvpvrcvRYIARknwfvsgsdd
evsetpvraakfvprknwiitgadd
Sc_YGL137W
Kl_KLLA0B01958g
Ca_CAL0005039
Yl_YALI0C21802g
Af_AFUA_2G10610.t1
Nc_NCUT_07117
Sp_SPBC16C6.13c
Cn_cn02021
Ro_RO3T_06159
Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP
47 1 CI YLR180W
SAM1
286
-
-
-
-
298
-
301
286
kvdrsaayaaRWVAKslvaaglckr
.........................
.........................
.........................
.........................
kvdrsaayvgRWIAKslvaaglarr
.........................
kvdrsaaytaRWIAKslvaaglarr
kvdrsaaytaRWIAKslvnaklcrr
Sc_YLR180W
Kl
Ca
Yl
Af
Nc_NCUT_02041
Sp
Cn_cn01393
Ro_RO3T_03742
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
48 1 C YBR038W
CHS2
576
531
633
596
650
952
-
652
462
cwelvakrdaKWVLKyvkeatgetd
cwelvakrdeawvlkyvkeatgetd
cwelvskrndnwvlkfvksatgetd
cwelvaklnekwmlkyvpsatgetd
cwelvakreeRWVLKfvksavgetd
cwelvakrgeRWVLKyvkgctgetd
.........................
cwelvskrqckwklhyvksayaitd
cyelvakkeanwvlhyvsssygetd
Sc_YBR038W
Kl_KLLA0D03542g
Ca_CAL0002701
Yl_YALI0B16324g
Af_AFUA_4G04180.t1
Nc_NCUT_05007
Sp
Cn_cn03728
Ro_RO3T_16229
Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis
49 1 CI YPR080W
TEF1
421
-
421
-
-
-
421
-
421
eafseypplgRFAVRdmrqtvavgv
.........................
eaftdypplgRFAVRdmrqtvavgv
.........................
.........................
.........................
eaftdyaplgRFAVRdmrqtvavgv
.........................
eaytdypplgRFAVRdmrqtvavgv
Sc_YPR080W
Kl
Ca_CAL0004916
Yl
Af
Nc
Sp_SPAC23A1.10
Cn
Ro_RO3T_15046
Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes
50 1 CI YGR240C
PFK1
876
854
897
-
691
-
-
-
-
psskdrvtasRFAVKcikfieqwnk
psskdrviasRFAVKcvkfieqwnk
psandrvmavkfslkamefietrng
.........................
pspmdriralrmavkcmlhlenyag
.........................
.........................
.........................
.........................
Sc_YGR240C
Kl_KLLA0A05544g
Ca_CAL0003055
Yl
Af_AFUA_4G00960.t1
Nc
Sp
Cn
Ro
Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
51 1 CI YDR208W
MSS4
492
413
436
839
481
381
375
497
253
gsffyysrdyKYIIKtihhsehihl
gsffyfsrdyKYIIKtihhsehkhl
gsffyysrdfRFIIKtihhsehkql
gsffyfsrdyRFIIKtihhsehkql
gsffyfsrdyKYIIKtihhsehkll
gsffyfsrdyKYIIKtihhaehkfl
gsffyfsrdyRFIIKtihhsehkfl
gsffyfsrdyRFIIKtiahsehkfl
gsffyysrdyRFIIKtihytehkfm
Sc_YDR208W
Kl_KLLA0A04301g
Ca_CAL0002340
Yl_YALI0F23573g
Af_AFUA_3G06080.t1
Nc_NCUT_03131
Sp_SPAC19G12.14
Cn_cn01363
Ro_RO3T_04373
Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation
52 1 C YBR245C
ISW1
89
27
25
-
-
66
-
-
-
pphdpesnkkRYLLKd---angk-k
pnsiae-kkeryllplrdlasgkrk
----rnklsfqdnaskyftktekqq
.........................
.........................
pvdgrrkrseanqlrrsifgkkhdr
.........................
.........................
.........................
Sc_YBR245C
Kl_KLLA0F06710g
Ca_CAL0001816
Yl
Af
Nc_NCUT_03554
Sp
Cn
Ro
Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation
53 1 C YMR176W
ECM5
692
741
813
741
786
757
573
-
540
lrfssea--akwtskmgflpgldvn
vnnipda--elwraenkllpsilpf
lnyales--eKWLAKqniipgfstf
ldg-paqecaslyskysqlpafsye
epwgamg--verlqafrrhpcfshd
epfghag--verlqtfrrqpcfshd
ikdgllnssisvlksmripssvsye
.........................
vdyglec--vkrykefrrqpcfshd
Sc_YMR176W
Kl_KLLA0C16203g
Ca_CAL0001611
Yl_YALI0C16390g
Af_AFUA_5G03430.t1
Nc_NCUT_04019
Sp_SPBP19A11.06
Cn
Ro_RO3T_13099
Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks
54 1 C YPL106C
SSE1
623
623
626
619
-
-
632
626
615
-degfdsikaKYIAKyeelaslgni
-ddgydstkgKYIAKyeelasignv
-edgedstkaKYIAKyeelasignv
-gagedakkalyiakyeelasignl
.........................
.........................
-eegedttkavytakledlmrvggp
sedgedatksayvqkldalkamgdp
-degydasksvyveklealkkignp
Sc_YPL106C
Kl_KLLA0E24597g
Ca_CAL0001523
Yl_YALI0E13255g
Af
Nc
Sp_SPAC110.04c
Cn_cn13198
Ro_RO3T_06487
ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm
54 2 C YPL106C
SSE1
641
641
644
637
-
-
650
644
633
laslgniirgRYLAKeeekkqairs
lasignvirgRYLAKeeekkqalra
lasignvikgRYLAKeqekkeqyrq
lasignlikgrynakqeeerqakva
.........................
.........................
lmrvggpirqryldaeeakrqk---
lkamgdpivlrwkesedrpraaaal
lkkignpvveryreaeerphaeral
Sc_YPL106C
Kl_KLLA0E24597g
Ca_CAL0001523
Yl_YALI0E13255g
Af
Nc
Sp_SPAC110.04c
Cn_cn13198
Ro_RO3T_06487
ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm
55 1 C YNL248C
RPA49
241
238
220
234
290
277
257
256
249
lelfpyqnnsKYVAKkldsltqp--
leyfpyt-kfqyvanklptltqa--
leklpft-ksefiakqlpilisq--
vdmlpyr-tsqmvrdslykitdkt-
-aglpvattsryvsrrveavvksg-
lediqvp--sRFVAKrvsnvassd-
akllpyr-hslfinerfqrllsie-
asalpykrsswlqyksravanikdk
kshlayr-dskfindrlmaiiaasg
Sc_YNL248C
Kl_KLLA0C02959g
Ca_CAL0004338
Yl_YALI0E05225g
Af_AFUA_5G06280.t1
Nc_NCUT_06254
Sp_SPAC2F3.03c
Cn_cn02440
Ro_RO3T_15617
RNA polymerase I subunit A49
56 1 C YBL037W
APL3
73
58
56
54
50
66
52
51
0
hdrlggyqrkKYVAKlayiyitsnt
-sglngyqrkKYVAKmayiyittna
--nlngyqkkkyvckliyiylignp
--nlsgyqkkkyvgkllyiyilg--
--nlngyqkkkyvckllyvyiqg--
--slsgyhkkkyvckllyiyilg--
--tlsaydrkkyvskllyiymlg--
--nldgyqkkKYLAKvvftyilg--
------------------myilg--
Sc_YBL037W
Kl_KLLA0B12243g
Ca_CAL0004290
Yl_YALI0C18623g
Af_AFUA_4G04310.t1
Nc_NCUT_02613
Sp_SPBC691.03c
Cn_cn07414
Ro_RO3T_03040
Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport
57 1 CI YFR019W
FAB1
2055
1833
2402
1818
2256
2296
1709
2197
1997
gsgflktlddRFIIKelshaeleaf
gsaflktlddRFVIKelshseldaf
gssflktldnRYILKelskselesf
gsaflktlddrlvvkqlspaeldaf
nslflktlddRFILKslspietqaf
ksvflktlddrlvmkslspvetsaf
gsaflktfdkKYILKvlsrlesdsl
gsaflksrddRFIAKeitryemdal
gsaflktkddrllmkqmskyeldaf
Sc_YFR019W
Kl_KLLA0D04598g
Ca_CAL0005404
Yl_YALI0E29161g
Af_AFUA_6G07440.t1
Nc_NCUT_01238
Sp_SPBC3E7.01
Cn_cn04307
Ro_RO3T_10566
1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis
58 1 C YNL193W
YNL193W
455
377
428
-
399
-
367
-
-
lvnssdnelrRYAIKeste-----k
minradnelsrcllkqtelnqlqgq
iiaradielqrssinnyss------
.........................
hmargdvemhrwrlglapwey----
.........................
lisradleiqr--------------
.........................
.........................
Sc_YNL193W
Kl_KLLA0F20944g
Ca_CAL0001137
Yl
Af_AFUA_5G04150.t1
Nc
Sp_SPAC926.02
Cn
Ro
Putative protein of unknown function; exhibits a two-hybrid interaction with Yhr151cp in a large-scale analysis
59 1 CI YHR059W
FYV4
85
78
104
75
92
-
80
-
-
ekgvn-iqqrKYILKqvhnyr----
ekgip-iqqrryilnqveklr----
nmgid-trarRYLLRwrhkfln---
ekgie-ardrryimtqlyryk----
evgieparqrRYLLRkrekfrqgiy
.........................
kegid-vrtrkyiasqrnrfk----
.........................
.........................
Sc_YHR059W
Kl_KLLA0C10164g
Ca_CAL0004161
Yl_YALI0E32747g
Af_AFUA_7G03730.t1
Nc
Sp_SPBC4B4.11
Cn
Ro
Protein of unknown function, required for survival upon exposure to K1 killer toxin
60 1 C YKL028W
TFA1
14
14
10
9
9
9
13
20
0
piddivknllKFVVRgfyggsfvlv
pieetikallsfvirqfypnsyvlv
-mddsvrslirfvsrgfystpyvli
--mdnikrllqyvtrgfydtksilv
--mdlantlirtvvrafyetrqili
--mdiaktlircvmrafystqeili
napeivqrlikmimrafyetrhiif
eiqklcsdlvyqvaysfydvpyiii
-------------------------
Sc_YKL028W
Kl_KLLA0E18657g
Ca_CAL0005399
Yl_YALI0F26367g
Af_AFUA_2G08450.t1
Nc_NCUT_04339
Sp_SPAC458.07
Cn_cn03337
Ro_RO3T_01562
TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening
61 1 CI YLR106C
MDN1
1276
1275
1287
1177
1268
1300
1094
1290
-
nsfatlrdlfRWALRdavgyeqlaa
nsfatlrdlfRWALRpavgyeelaa
nsfatlrdlfrwamrdavgyeelaa
-afatlrdlfrwagrncdnneelam
nsfatlrdlfRWALRraddreqlav
nsfatlrdlfRWALRaaetrqdiad
nsfatlrdlfrwafreavgyqqlae
qsfatlrdlfrwaergaigyqqlae
.........................
Sc_YLR106C
Kl_KLLA0F19888g
Ca_CAL0003858
Yl_YALI0B08338g
Af_AFUA_2G12150.t1
Nc_NCUT_06238
Sp_SPCC737.08
Cn_cn10211
Ro
Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm
62 1 CI YBR108W
YBR108W
27
28
-
-
-
-
-
-
-
sagkygyqgtKYVAKtgykaskkhy
sagkygyqgtKYVAKagykaskthy
.........................
.........................
.........................
.........................
.........................
.........................
.........................
Sc_YBR108W
Kl_KLLA0B09460g
Ca
Yl
Af
Nc
Sp
Cn
Ro
Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
63 1 C YJL012C
VTC4
296
297
304
295
308
338
294
342
891
dwtgeksvkaRFALKerhvndflkg
dwtgeksvkaRFALKekyvndflhg
dwtgeksvkaRFALKekkvnqflsg
dwtgeksvkarfnlkekhvndfmag
dwtgeksvkarfslkekhvnaylsg
dwtgeksvkaRFALKeklvnpylrg
dwtgeksvkarfplkekyvnaflrg
dwtgeksvkerftikegkmndfisg
swtgeksvkarfpikekylnaflkg
Sc_YJL012C
Kl_KLLA0F22627g
Ca_CAL0004171
Yl_YALI0C10945g
Af_AFUA_2G09040.t1
Nc_NCUT_09629
Sp_SPCC1322.14c
Cn_cn04250
Ro_RO3T_16785
Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion
64 1 C YOL129W
VPS68
136
128
134
136
126
132
123
141
129
lsgsivvliiKFLVKdyntyptlgm
isgslvvlivKFLLKdytsyptlgm
lagsfmvfilkylmnhy-tfptlgm
massiavlvlkyalpgy-smptlgm
lagsvtvmvlKYLIKqy-plptlyf
maggvtvfvlKYVVKdv-gfpalrm
lggsftvfilkyvvagy-egksllm
lagslcvlilkyivpdytg--ytyy
lagsccvlivkyiihldssqpyiny
Sc_YOL129W
Kl_KLLA0E07415g
Ca_CAL0005014
Yl_YALI0D20944g
Af_AFUA_6G04760.t1
Nc_NCUT_03901
Sp_SPBC8D2.02c
Cn_cn02565
Ro_RO3T_00165
Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria
65 1 CI YMR109W
MYO5
520
518
532
521
553
520
525
526
518
tnphfdlrsnKFVIKhyagdvtydi
tnahfdlrssKFVIKhyagdvtydi
snrhfedrrgKFIIKhyagdvtydv
qnphfeqrqrKFVIKhyagdvtydv
-npnfenrqgqfiikhyagdvsyav
-nphltprqgafivkhyagdvtysv
-nphfeqrqnqfivkhyagdvtysi
-npnfeargnKFLIKhyagdvlytv
-nphfesrgsKFLIRhyagdvlyni
Sc_YMR109W
Kl_KLLA0B12562g
Ca_CAL0001808
Yl_YALI0E02046g
Af_AFUA_8G05660.t1
Nc_NCUT_01269
Sp_SPBC146.13c
Cn_cn09230
Ro_RO3T_15775
One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization
66 1 CI YML098W
TAF13
69
69
83
73
-
75
74
-
78
qrnklrledfKFALRkdpiklgrae
krnkikvedfRFVLRkdevklgrae
nrtrvklndlaftlrndpmklarfr
grqkikvddfKFLLRndprklgrae
.........................
grqkvkfedfefamrrnprfmgkiq
-rnkvkvddfKFALRddpkklgrve
.........................
-rgkvkvedfKFVLRkdtkklarve
Sc_YML098W
Kl_KLLA0D10219g
Ca_CAL0002660
Yl_YALI0D09625g
Af
Nc_NCUT_02632
Sp_SPCC1494.02c
Cn
Ro_RO3T_03275
TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors
67 1 CI YDL164C
CDC9
300
251
314
285
434
433
300
337
243
-------ieaKFLIRslesklrigl
-------yeaKFLIRslesklrigl
-------seaKFLIRslqgklrigs
-------neaKFIIRslegklrigl
--------eaKFIVRflegklrlgl
tkdkggpseaKFIVRflegklrlgl
--------epKYLIRalegklrlql
--------eaKFIIRslegklrigl
--------eaKYIIRqlegklrigl
Sc_YDL164C
Kl_KLLA0D12496g
Ca_CAL0006047
Yl_YALI0F01034g
Af_AFUA_2G09010.t1
Nc_NCUT_06250
Sp_SPAC20G8.01
Cn_cn08403
Ro_RO3T_07347
DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination
68 1 C YLR382C
NAM2
569
556
521
503
613
613
555
-
492
ehailhllysRFIAKflgsinawsd
ehailhllysrfiskftasigmwdg
ehailhllysRFIAKflsdcglwdg
ehailhllyaRFVAKfladkgywsg
ehailhllyarfiykflsqtelfpe
ehailhllysrfiykflmtssfagk
ehsilhllysrffskfmkdiglwng
.........................
ehailhllysrfiskvllkqgayqq
Sc_YLR382C
Kl_KLLA0E05325g
Ca_CAL0001358
Yl_YALI0F02299g
Af_AFUA_6G04910.t1
Nc_NCUT_03498
Sp_SPAC4G8.09
Cn
Ro_RO3T_15723
Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance
68 2 C YLR382C
NAM2
695
678
643
624
741
746
677
-
596
wdeskivgierwlqkvlhltknils
wdeskivgierwlermlkfc---is
wqeeqisgtdrwlrrviqlgdsite
wdegkivgikRWLLKvksitesvvk
wddtkivgierwfgrlwklvldakq
wdeskitgvtrwlsrvhdlvqkiac
wnenaimgtkrwltkiwncvhqlle
.........................
wddtsivgmqRWLAKvlkls-----
Sc_YLR382C
Kl_KLLA0E05325g
Ca_CAL0001358
Yl_YALI0F02299g
Af_AFUA_6G04910.t1
Nc_NCUT_03498
Sp_SPAC4G8.09
Cn
Ro_RO3T_15723
Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance
69 1 I YLR256W
HAP1
622
503
477
416
-
-
-
-
-
tpvealelcqKYLIKfdelssisnn
tpietveivrKFLIKfdeissfans
inidvvsvaqecfnqfnimr-----
awtewlkgidhcleqamvcvr----
.........................
.........................
.........................
.........................
.........................
Sc_YLR256W
Kl_KLLA0F22990g
Ca_CAL0002550
Yl_YALI0C18667g
Af
Nc
Sp
Cn
Ro
Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus
70 1 CI YLR089C
ALT1
124
62
48
40
38
22
-
48
-
edvnenvlkaKYAVRgaipmraeel
ddvnenvlkaKYAVRgripmraeel
hdinpqtveaKYAVRgkipiiadel
kdlnpqvvnaqyavrgklavradei
dninpnvkaaKYAVRgelavkaeey
dninphvraaKYAVRgelavkseef
.........................
dtinpavqavhyavrgelaikadky
.........................
Sc_YLR089C
Kl_KLLA0F19162g
Ca_CAL0004796
Yl_YALI0D06325g
Af_AFUA_6G07770.t1
Nc_NCUT_03635
Sp
Cn_cn07331
Ro
Putative alanine transaminase (glutamic pyruvic transaminase); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
71 1 C YKR026C
GCN3
75
75
75
75
86
97
88
98
60
slragcdifmRFVLRnlhl------
slragcdifmRFVLKnthl------
slsagcdlfmRFVLRntnv------
slsagcdlfmRFVLRnire------
glsagtdlfqrylittlqrpgqlgp
pllagadlfeqyllrslrg----qt
slsagcdifqrfvtrslhd------
gvragcqlwerffalfpgv------
-------------------------
Sc_YKR026C
Kl_KLLA0F13970g
Ca_CAL0000120
Yl_YALI0C18161g
Af_AFUA_5G11340.t1
Nc_NCUT_05286
Sp_SPCC11E10.07c
Cn_cn03560
Ro_RO3T_06935
Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
72 1 C YHL030W
ECM29
363
352
384
316
361
359
301
-
243
klrsltlsfirhvaklnyknlnpas
rvklaalvfirhvaknnhlalrett
rlrslaiqfirklgqspvpeenlek
ysraaiiqfvnwivkhsneelflrh
klrtqiftfttwvvrmgsp-sdlkl
kvhralfefinwvarigaskpefsk
smqprliqftrwvvdkadpnflkpk
.........................
slspvapiivsgllkfinqleeaqg
Sc_YHL030W
Kl_KLLA0E00727g
Ca_CAL0004949
Yl_YALI0C03828g
Af_AFUA_6G06540.t1
Nc_NCUT_00776
Sp_SPAC1782.01
Cn
Ro_RO3T_02505
Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome
73 1 CI YDR502C
SAM2
288
288
289
290
291
-
286
-
-
kvdrsaayaaRWVAKslvaaglckr
kvdrsaayaaRWVAKslvhagickr
kvdrsaayaaRWVAKslvtaglakr
kvdrsaayaaRWVAKslvkaglarr
kvdrsaayvgRWIAKslvhaglarr
.........................
kvdrsaayaaRWIAKslvaaglarr
.........................
.........................
Sc_YDR502C
Kl_KLLA0C01782g
Ca_CAL0001034
Yl_YALI0B14509g
Af_AFUA_1G10630.t1
Nc
Sp_SPBC14F5.05c
Cn
Ro
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
74 1 CI YGR124W
ASN2
450
-
450
443
498
460
437
-
445
mikpkegrieKYILRkafdttdepd
.........................
liqp--gkieKYILRkafdtsdepd
iidk--dhiekysirkafdtsdepg
mitk--erieKYILRkafdtsdepd
mitk--ekleKYILRkafdtkdqpe
my--ingrkeKYILRkafdtthdss
.........................
lhdrsqgrmeKYILRkafddes---
Sc_YGR124W
Kl
Ca_CAL0003290
Yl_YALI0A13387g
Af_AFUA_4G06900.t1
Nc_NCUT_03787
Sp_SPBC119.10
Cn
Ro_RO3T_15933
Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
75 1 C YHR116W
COX23
91
62
74
60
-
-
-
36
-
ddpenpvnkyKFALKadsqyydpce
ddpestlnryRFAVKgaseyydpcq
dnpkshrhkykwsmkepskfydpce
ddptamsnrvqflakadsqyydpca
.........................
.........................
.........................
eipedykktfr-grgtvskfvdpce
.........................
Sc_YHR116W
Kl_KLLA0F24024g
Ca_CAL0003316
Yl_YALI0B10274g
Af
Nc
Sp
Cn_cn14137
Ro
Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p
76 1 C YPL125W
KAP120
763
762
745
745
775
1398
750
767
-
tfqdifkqmsKYLLKlredsfqlvl
afteilkhaasyllllrddsytill
laseifqvignylskmrddayaifi
-----htllsifgkymdilsfdvvq
rlpllvsfetllqsttrqrigvvpr
rrptlaalvktldarsreqsqtgar
-----ftifeklndllddvknetlq
---qaiasnlamalststgnesavi
.........................
Sc_YPL125W
Kl_KLLA0D06633g
Ca_CAL0003089
Yl_YALI0B00198g
Af_AFUA_1G03590.t1
Nc_NCUT_01223
Sp_SPCC1322.06
Cn_cn12143
Ro
Karyopherin with a role in the assembly or export of 60S ribosomal subunits
77 1 C YOR260W
GCD1
406
338
306
312
428
418
344
407
295
nnlnaymdanRFVLKiksqtmftkn
nslsaymesnRYVLKik-qtaiqqr
nnlpvlmeanryfmkkqaiaksasq
nnlsaymemnrvilkarakanataq
dtsalllsvslrlaklesieevg-r
dtaqlllqislqlaklpsieevgsa
nnlpnyfelnkciak----------
nslagywelnrrfikslssttpaak
ntiasyselnryvtk---------q
Sc_YOR260W
Kl_KLLA0C09570g
Ca_CAL0005825
Yl_YALI0E21846g
Af_AFUA_1G16660.t1
Nc_NCUT_02713
Sp_SPAC4D7.09
Cn_cn08385
Ro_RO3T_10989
Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression
78 1 CI YDL136W
RPL35B
115
-
-
-
-
-
-
-
115
rkkqiafpqrKYAIKa---------
.........................
.........................
.........................
.........................
.........................
.........................
.........................
qkkeahfplrKYAVKa---------
Sc_YDL136W
Kl
Ca
Yl
Af
Nc
Sp
Cn
Ro_RO3T_13637
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein
79 1 CI YJL187C
SWE1
469
421
-
447
-
754
592
820
-
---------kKYAIKaikp--nkyn
---------lKYAIKsvrp--tkhn
.........................
gssviltppnRYAVKkmkypfagpk
.........................
fssftstp-grhtpevekvfavkki
---------lKYAVKklkvkfsgpk
---------glwavkkargmfdgar
.........................
Sc_YJL187C
Kl_KLLA0B07579g
Ca
Yl_YALI0F01716g
Af
Nc_NCUT_03764
Sp_SPCC18B5.03
Cn_cn07077
Ro
Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate
80 1 C YDR421W
ARO80
698
684
842
773
758
817
-
749
-
rqgmlkympvRWVIRiirsiafivk
klkmlkympvrwvmrivrsivfmik
rfkmlrfmpvrlltrfiraaafivr
rmealkyapvRWVVRivhatvflfk
pgdhlkhapvrtcfrilsgmifilk
pkgylkhapvrtyfriisgamfllk
.........................
qmgslrylpsrylinisyaavfalk
.........................
Sc_YDR421W
Kl_KLLA0A01804g
Ca_CAL0001342
Yl_YALI0C18645g
Af_AFUA_5G13310.t1
Nc_NCUT_00452
Sp
Cn_cn08195
Ro
Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids
81 1 CI YMR162C
DNF3
1266
1185
1332
619
1163
1100
1280
-
-
rvsdysigqfRFLLKllfvhgryny
rssdysiaqfRYLLKllfvhgryny
rsadyaiaqfRFLLKlllvngryny
rssdfaiaqfsyllklllvhghwny
risdysiaqfRFLLKlllvhgrwny
risdfsisqfrflqrllfvhgrwny
rssdfsigrfKFLIKllfchgrwsy
.........................
.........................
Sc_YMR162C
Kl_KLLA0E01651g
Ca_CAL0003528
Yl_YALI0E04169g
Af_AFUA_4G10210.t1
Nc_NCUT_03292
Sp_SPAC821.13c
Cn
Ro
Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase
82 1 CI YDL140C
RPO21
403
403
403
408
418
417
409
419
-
rngpnehpgaKYVIRdsgdridlry
rngpnehpgaKYVIResgdridlry
rngpnehpgaKYVIRdtgdridlry
rngpnehpgaKYVIRdtgeridlry
angpnehpgaRYIVRdngeridlrh
qngpnehpgaKYVIRsdgsrvdlrh
rngpdehpgaKYIIRdtgeridlry
nngpatypgaryyvkdtgervdlky
.........................
Sc_YDL140C
Kl_KLLA0F05071g
Ca_CAL0000919
Yl_YALI0C16566g
Af_AFUA_1G14680.t1
Nc_NCUT_01261
Sp_SPBC28F2.12
Cn_cn05376
Ro
RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime
83 1 CI YPR145W
ASN1
451
451
-
-
-
-
-
467
-
--kegr--ieKYILRkafdttgepd
--aegk--ieKYILRkafdttdepd
.........................
.........................
.........................
.........................
.........................
vdedgrpkmeKYILRkafdcs--pe
.........................
Sc_YPR145W
Kl_KLLA0B10868g
Ca
Yl
Af
Nc
Sp
Cn_cn12090
Ro
Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
84 1 C YBL004W
UTP20
2062
2063
2075
2101
2129
2162
2067
2175
2288
qskgrlekqfkfmvdnlqyptesgr
qskgrlekqfrfmlnnlqypsqegr
qgkgrlekqfkylvsnltypteegr
qsrdrlnaefqflihnldypfdsgr
qaknrwakqlsflaknldykhqegr
qkrnrwekqlkfivanlkyereggr
qgktrlskqisfilknleyefapgr
qgkgrlksqmtffaqnlqytyeagr
qgkgrlkkqmsfiiknlefefesgr
Sc_YBL004W
Kl_KLLA0E17425g
Ca_CAL0002346
Yl_YALI0D22440g
Af_AFUA_6G08240.t1
Nc_NCUT_02205
Sp_SPBC56F2.04
Cn_cn12221
Ro_RO3T_14432
Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA