Regulatory Genomics Special Interest Group (RegGenSIG)
Special Interest Group (SIG) at ISMB 2013
July 20, 2013, Berlin, Germany
In conjunction with The Twenty-first International Conference on Intelligent Systems for Molecular Biology (ISMB)

The RegGenSIG meeting focuses on bioinformatics for regulatory genomics, fostering a collaborative community wherein scientists convene to discuss difficult research problems in computational regulatory genomics.

POSTER PRIZES

F1000Research supports the poster session with three poster prizes, each consisting of a free one-year subscription to F1000Prime (worth $250) and a free submission to F1000Research (worth $1000).

Program

Download as PDF, with abstracts

07:30		Registration
08:30	5 min	Welcome to SIG
Session Chair, Jason Ernst	40 min	Keynote Stein Aerts, University of Leuven, Belgium Motif-based identification of master regulators and direct TF-target interactions in human and Drosophila gene networks
	15 min	Ivan Kulakovskiy, Russian Academy of Sciences, Moscow, Russia diChIPMunk: utilizing ChIP-Seq data to construct advanced dinucleotide models of transcription factor binding sites
	20 min	Erik van Nimwegen, Basel University, Switzerland The transcription factors democracy: Completely automated inference of genome-wide regulatory interactions from sequencing data
	20 min	Alan Moses, University of Toronto, Canada Systematic identification of conserved non-coding sequences in plants
10:15	30 min	Morning Coffee Break
10:45 Session Chair, Kathleen Marchal	15 min	Sunil Kumar, Swiss Inst. for Exp. Cancer Research, Switzerland Predicting CTCF site occupancy using sequence and chromatin-associated features
	20 min	Struan FA Grant, University of Pennsylvania, USA Following functional clues based on the genetic commonalities of diabetes and cancer
	15 min	Anirban Bhar, Georg August University, Göttingen, Germany Revealing exclusive usage of T-BOX family paralogous transcription factors through identifying diversity in expression profiles during hiPSC-derived cardiomyocytes generation
	15 min	Felicia Ng, Cambridge Institute for Medical Research, UK Shared transcription factors contribute to stage-specific transcriptional programs during blood cell differentiation
	20 min	Andrea Califano, Columbia University, USA Assembly and interrogation of tumor-specific regulatory models reveals master regulators of tumor maintenance and chemosensitivity
	15 min	Anna Lyubetskaya, Boston University, USA Reconstructing the regulatory network of TB: Transcription factor binding distribution and properties
12:30	60 min	Lunch / Poster Session
13:30 Session Chair, Struan Grant	40 min	Keynote Ben Lehner, Centre for Genomic Regulation, Universitat Pompeu Fabra, Barcelona, Spain The genetics of individuals: Why should a mutation kill me, but not you?
	15 min	María Rodríguez Martínez, Columbia University, USA GWAS next generation: identifying mechanisms of action in association studies
	20 min	Boris Lenhard, Imperial College London, UK Alternative and overlapping determinants of transcription start site selection in vertebrate promoters
	20 min	Johannes Söding, Ludwig Maximillian University, Germany Drosophila Pol II core promoters cluster into four classes characterized by distinct sets of motifs, regulatory properties, and nucleosome patterning
	20 min	Jason Ernst, UCLA, USA Interplay between chromatin state, regulatory binding, and regulatory motifs
15:30	30 min	Afternoon Coffee Break / Posters
16:00 Session Chair, Johannes Söding	20 min	Bartek Wilczyński, University of Warsaw, Poland Predicting regulatory domain boundaries from chromatin immunoprecipitation data
	15 min	Guo-Cheng Yuan, Dana-Farber Cancer Institute, USA Prediction of chromatin state variability from genomic sequence
	15 min	Jan Hapala, Masaryk University, Brno, Czech Republic Rotational positioning of regulatory elements within nucleosomes
	15 min	Idit Kosti, Israel Institute of Technology, Haifa, Israel Does intragenic DNA methylation determine differential exon expression?
	15 min	Christoph Kaleta, University of Jena, Germany Survival of the quickest — Identification of time-optimal regulatory strategies of metabolism in Escherichia coli
	15 min	Lieven Verbeke, Ghent University, Belgium EPSILON: localized networks for eQTL prioritization
	15 min	Sridhar Hannenhalli, University of Maryland, USA Enhancer networks — Hidden layer of gene regulation
	5 min	Concluding remarks on SIG
18:00		SIG Ends

SIG Chairs:

Finn Drabløs, Norwegian University of Science and Technology, Norway, finn.drablos@ntnu.no
Eileen Furlong, EMBL, Germany, eileen.furlong@embl.de
Saurabh Sinha, University of Illinois, USA, sinhas@illinois.edu
Lonnie R. Welch, Ohio University, USA, welch@ohio.edu

SIG Organizing Committee:

Tim Bailey, University of Queensland, Australia
Harmen Bussemaker, Columbia University
Andrea Califano, Columbia University
Julio Collado-Vides, National Autonomous University of Mexico
Laura Elnitski, National Human Genome Research Institute, USA
Ana Teresa Freitas, Technical University of Lisbon, Portugal
Roderic Guigo, Centre for Genomic Regulation, Spain
Alexander Hartemink, Duke University
Manolis Kellis, MIT, USA (pending)
Kathleen Marchal, Professor University of Ghent and K. U. Leuven, Belgium
William Noble, University of Washington (tentative)
Isidore Rigoutsos, Thomas Jefferson University, USA
Sophie Schbath, Institut National de la Recherch? Agronomique, France
Gustavo Stolovitzky, IBM
Gary Stormo, Washington University, USA
Kai Tan, University of Iowa, USA
Andrei Thomas-Tikhonenko, University of Pennsylvania
Esko Ukkonen, University of Helsinki, Finland
Martin Vingron, Max Planck Institute for Molecular Genetics, Germany
Weixiong Zhang, Washington University, USA
Igor Zwir, University of Granada

RegGenSIG is an activity of the ISCB Special Interest Group for Regulatory Systems Genomics, (http://www.iscb.org/iscb-sigs-regsys), a community of shared interest that has multiple activities and interactions throughout the year, rather than solely meeting during the ISMB conference. An important goal of the SIG is to foster a topically-focused collaborative community wherein scientists communicate with one another on research problems and/or opportunities in the area of computational biology as it pertains to regulatory and systems genomics. The SIG holds two meetings per year, (1) RegGenSIG and (2) The RECOMB Conference on Regulatory and Systems Genomics and DREAM Challenges (http://iscb.org/recomb-regsysgen2013).