confind (c) Finn Drablos, NTNU 2007,2012 Version 02.10.2012 Program started Mon Jul 06 12:52:42 CEST 2015 ---------- Configuration file for PIP motif Version FD 02-10-2012 Datasets are from Inparanoid 7.0. Gene descriptions are taken from Inparanoid 7.0. Localisation data are from eSLDB. Using K as equivalence for KR in consensus Using F as equivalence for FYW in consensus Using L as equivalence for LVI in consensus ---------- Found 5884 sequences in ./lib/S.cerevisiae.fa Got match in 183 sequences against pattern Q..[ILM]..[FHD][FY] Removed 0 entries with no info in ./ref/eSLDB_Saccharomyces_cerevisiae_TS.txt matching .* There are 183 entries left Found 146 orthologs in Kl (Kluyveromyces lactis) Found 123 orthologs in Ca (Candida albicans) Found 115 orthologs in Yl (Yarrowia lipolytica) Found 106 orthologs in Af (Aspergillus fumigatus) Found 110 orthologs in Nc (Neurospora crassa) Found 98 orthologs in Sp (Schizosaccharomyces pombe) Found 88 orthologs in Cn (Cryptococcus neoformans) Found 89 orthologs in Ro (Rhizopus oryzae) Removed 23 entries without orthologs There are 160 entries left Created 139 new sequence files Added 734 new orthologs to these sequence files Ran ClustalW on 139 library files Removed 86 sequences where pattern was not conserved There are 74 entries left Missing information on gene for 0 proteins Removed 0 duplicate sequences representing the same gene There are 74 entries left Description is missing for 0 genes ---------- Pro - Protein number (green if on priority list) # - Motif number i protein CI - Entry is accepted according to Consensus or Individual pattern hits Protein ID / Gene ID - IDs from input data Pos - Position of motif in sequence Alignment - Alignment of motif (UPPER case) and flanking region (lower case) lower case only - no hit by motif, "-----" - gaps, "....." - missing protein Ortho ID - ID of Orthologs, with organism code (see above) Description
Pro | # | CI | Protein ID Gene ID |
Pos | Alignment | Ortho ID | Description |
---|---|---|---|---|---|---|---|
1 | 1 | I |
YDR051C YDR051C |
250 238 156 144 - - - - - |
advydrvasfQETLFRHFhdrqerrprd advydrcsgfQESLFRHFeksggkk-rd advydrvasfmeslfrqfrsd---dfpn advydrcagfnetlfrqfnsd---kfps ............................ ............................ ............................ ............................ ............................ |
Sc_YDR051C Kl_KLLA0F18810g Ca_CAL0004865 Yl_YALI0F11781g Af Nc Sp Cn Ro |
Protein of unknown function; interacts with Hsp82p in two-hybrid assay; deletion confers sensitivity to Nickel |
2 | 1 | C |
YPL091W GLR1 |
241 240 272 226 221 221 222 235 227 |
tvlrkfdeciQNTITDHYvk-eginvhk tvlrkfddciqetvtdtyik-egvnihk tvlrsfdeviqntvtdyyidnlginihk tvlrafdimiqdtitdyyvk-eginvlk tmlrkfdpmiqktmteryea-tgvhihk tflrsfdpmiqqvsvkeyer-igvkvhk kflrkfdpiisdgimdhfqh-iginvht qllrtfdpmmsevlvpcmek-agmkihk qilrkfdsvikdnllaqmqa-vginfvf |
Sc_YPL091W Kl_KLLA0E24069g Ca_CAL0005719 Yl_YALI0E18029g Af_AFUA_1G15960.t1 Nc_NCUT_02517 Sp_SPBC17A3.07 Cn_cn05155 Ro_RO3T_00021 |
Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione |
3 | 1 | C |
YGL125W MET13 |
234 234 229 230 229 229 229 233 229 |
aaflrraqwgQISIPQHFssrldpikdd psfirrtqwcqinvpdnflellepvkdd aafirrakwseiaipqhfldaldpikdd asfmrranwcQIQIPQDFldqlepvkdd aafirranwtkarippdwlealepvknd asfirranhmnckipeewmaklepvknd dsfirrakwsgvkipqhfmdtlvpvkdd ekfekwvqreniivpshfyealnpvrgd sglkrviafndnfvpqkiwdelesiked |
Sc_YGL125W Kl_KLLA0F09647g Ca_CAL0004097 Yl_YALI0B00572g Af_AFUA_2G11300.t1 Nc_NCUT_08042 Sp_SPAC56F8.10 Cn_cn09202 Ro_RO3T_02980 |
Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway |
3 | 2 | C |
YGL125W MET13 |
570 573 578 554 554 555 558 560 553 |
ydkphsaqfiqsliddyclvnivdndyi hkatesvnlvnhiidnyvlinvvdndfi tqvdefvqlmkkfgdefvlcnlvnndfv paesesrkflddifnnwylvnivhndfh dasspsrkliqdimdnwylvnivnndfh dadtpsrllieeimdkwylinivnndfh spdsisrkllvsmmkewflcvivdndfq paespsrklitdtmntsylvnivandfr eresesaelildvtnnyylinivhndfq |
Sc_YGL125W Kl_KLLA0F09647g Ca_CAL0004097 Yl_YALI0B00572g Af_AFUA_2G11300.t1 Nc_NCUT_08042 Sp_SPAC56F8.10 Cn_cn09202 Ro_RO3T_02980 |
Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway |
4 | 1 | CI |
YPL082C MOT1 |
1532 1547 1562 1536 1564 1562 1618 1541 1539 |
qdyycelgdlQKQLYMDFtkkq------ qdyycelsdlQKQLYNDFvkkq------ qdyycelsdlQKKLYKDFaktq------ qdyycelselQRELYGDFakkq------ qnyycdpselQRKLFEDFtkke------ qnyycdlsdlQRKLFEDFtkre------ qdyycdmsdlQRKLLNDFvsqlnineel qdyycelspvqqqlyeefsrsk------ qdyycelsdlqkslyeefaksqakn--s |
Sc_YPL082C Kl_KLLA0E23717g Ca_CAL0002614 Yl_YALI0F31053g Af_AFUA_1G05830.t1 Nc_NCUT_07891 Sp_SPBC1826.01c Cn_cn05478 Ro_RO3T_12365 |
Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity |
5 | 1 | CI |
YDL001W RMD1 |
257 271 304 237 361 377 210 309 186 |
efnyyvtksyQPRIYNDFitlrdgsnym qfnyyitqsyQPRIYNDFitlrdgsnym efnyyitksyQPRIYNDFitlrdddnym efnyyitqsyQPRIYNDFitlrdgrnym nfnfyyareyQARIYNDFislrdprnhm yfnfyytheyQARIYNDFitlrdknnym efnyyittlyQPRIFNDFialrdasnym dlnfyyad--ysriyndvitlrkgssym efhyyynesyqpriyndiitlrnptnyl |
Sc_YDL001W Kl_KLLA0E17381g Ca_CAL0002345 Yl_YALI0B05390g Af_AFUA_2G12110.t1 Nc_NCUT_07893 Sp_SPCC16C4.01 Cn_cn13172 Ro_RO3T_02150 |
Cytoplasmic protein required for sporulation |
6 | 1 | CI |
YKL166C TPK3 |
160 217 - - - - - - - |
rmwgtfqdsqQVFMVMDYieggelfsll rmwgtfqdsqQLFMIMDYieggelfsll ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YKL166C Kl_KLLA0B07205g Ca Yl Af Nc Sp Cn Ro |
cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p |
7 | 1 | C |
YPL026C SKS1 |
69 64 123 - - - 53 - - |
nsqvarttllQTQLYHFFksfqkklflp etslkksavlqtqlyhyfksfqnklflp ghkgessmnkqiisqefyqyflnnsmpq ............................ ............................ ............................ ---------------------------- ............................ ............................ |
Sc_YPL026C Kl_KLLA0D12100g Ca_CAL0000440 Yl Af Nc Sp_SPBC19C2.05 Cn Ro |
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway |
8 | 1 | CI |
YJL033W HCA4 |
543 541 541 536 547 551 530 623 467 |
kydkmferknQTILSEHYlnitkaqa-- rydkmferknQTVLSEHYlnvtkaqa-- kydrmferknQTILSDHYlnmtgnkv-- kmdrmferknQNVLSDHYlnmvkgda-- kydrmferrnQDVLAEHYsklinddgtm kydkmaerqnQDVLSTHYrkllged--- kydriferknqdvlaahrqrlvevns-- kydrmferknQSILTPHYtaliahdadn kydrmfqrknQDILSEHYnklvdyeg-- |
Sc_YJL033W Kl_KLLA0D09504g Ca_CAL0004182 Yl_YALI0A20328g Af_AFUA_6G11070.t1 Nc_NCUT_05189 Sp_SPAC1093.05 Cn_cn01736 Ro_RO3T_01386 |
Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis |
9 | 1 | C |
YLR067C PET309 |
385 383 472 - - - - - 300 |
rgmiptyavlQSLLYAHYkvgdfaacfs rdmtpsyavllsiinahynvgdyngavr rglhlnstvmdalirskirlldqtkvie ............................ ............................ ............................ ............................ ............................ kkikpdevtygtwidakkragdlegald |
Sc_YLR067C Kl_KLLA0D05423g Ca_CAL0006262 Yl Af Nc Sp Cn Ro_RO3T_11224 |
Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; located in the mitochondrial inner membrane |
10 | 1 | C |
YKR058W GLG1 |
189 - 188 173 - - - - - |
---tsidgsdQGILNQFFnqn------- ............................ npnvsfdgadqgllnqyfnaqpdwvqal --gisfdggdqgllneyfr--------- ............................ ............................ ............................ ............................ ............................ |
Sc_YKR058W Kl Ca_CAL0004098 Yl_YALI0C21065g Af Nc Sp Cn Ro |
Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin |
11 | 1 | C |
YJL005W CYR1 |
1812 1671 1473 1814 1894 2036 1476 2049 1285 |
arvqgvadggQIAMSSDFysefnkimky arvsgiadggQVMLSNDFmvefkkilsy srisaiadggqiavssdfldvlnsltvk arvsavadggqitvsadfiskvkklqsl srisavadggqifvssdfmsdiqrnlev srisavadggqitassdfiteihrclet srvvsvadggqiavsaevvsvlnqldse arinasadggqlmasqdvlneiaplmey sricnaadggqicissdviaalrempgv |
Sc_YJL005W Kl_KLLA0F15708g Ca_CAL0002580 Yl_YALI0B18759g Af_AFUA_6G08520.t1 Nc_NCUT_06446 Sp_SPBC19C7.03 Cn_cn07108 Ro_RO3T_02871 |
Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation |
12 | 1 | C |
YNL083W SAL1 |
298 270 337 304 338 384 182 423 249 |
lakavkslyrQGGIKAFYvgnglnvikv likaattlyrQGGLRAFYvgnglnvvkv ivqavrtlwrQGGIKAFYvgnglnvmkv linaikniwaeggirsffignglnvfkv lvgavkelwraggirslfagnglnvvkv iydairtlwraggiktffagnglnvvki llhttkvlwnrngirsffvgnginvlkv wgavqriymeggglrafwvgnglnvtki ---lkniyhqgggfraffvgnglnviki |
Sc_YNL083W Kl_KLLA0C11363g Ca_CAL0004453 Yl_YALI0E10813g Af_AFUA_2G15780.t1 Nc_NCUT_01705 Sp_SPBC12D12.05c Cn_cn03024 Ro_RO3T_00735 |
Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains |
13 | 1 | C |
YJL024C APS3 |
13 13 13 13 13 13 13 13 13 |
havlifnkkcQPRLVKFYtpvdlpkqkl havlifnkkcQPRLIKFYtpvevekqtl hsvlifnndglprlmkfytkvdiptqkl hsvlifnnsglprltkfyapvdlatqqt navlvfnnngQPRLTKFYtqidtqtkqs naflvfngqgQPRLTKFYtqldtsiqqr yavfifnnkgkprltkfytpidesiqqk havlifntngkprlskfftplpplvqqs ksvlifnnhgkprlikfyqqidiatqqa |
Sc_YJL024C Kl_KLLA0F15268g Ca_CAL0004948 Yl_YALI0E29733g Af_AFUA_6G13020.t1 Nc_NCUT_09317 Sp_SPAC30D11.05 Cn_cn06383 Ro_RO3T_16249 |
Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function |
14 | 1 | C |
YGL131C SNT2 |
174 192 201 123 284 380 144 0 56 |
ttsvfpakffQVRMNWFYrprdiqehvn latsfpaiyfqlkmnwyyrprdiqertn manivdaknynfqiqwfyrprdisktts prqkypasqflfqvnwfyrpkdiskhva -------piealrvnwyyrprdihriva -------pvdalrvnwyyrpkdigrrvq -------lydsvrlnwyfrprdiqrhlt ---------------------------- ------rkglqariawfnrpkdvinrks |
Sc_YGL131C Kl_KLLA0B02178g Ca_CAL0002960 Yl_YALI0E30547g Af_AFUA_1G05240.t1 Nc_NCUT_07306 Sp_SPAC3H1.12c Cn_cn04066 Ro_RO3T_01596 |
DNA binding protein with similarity to the S. pombe Snt2 protein |
15 | 1 | CI |
YBL040C ERD2 |
194 193 187 192 201 190 187 188 110 |
dkiaffagllQTLLYSDFfyiyytk--- dklsvftgviqtlvysdffyiyyqk--- dfvsvlagllQTGIYSDFfyiyytk--- nlvafiggiiQTVIYSDFfyvyyvk--- dpiamifgivqtafyvdfawvyysrqrv dyiavaagiiQTLLYTDFfwvyytt--- igvailagiiQTVLYGDFavvyrrt--- daiavvagiiQTAIYADFgyiyvtr--- ewvscvagllQTALYSDFfyiyynr--- |
Sc_YBL040C Kl_KLLA0E05611g Ca_CAL0004240 Yl_YALI0D06545g Af_AFUA_2G02980.t1 Nc_NCUT_06835 Sp_SPBP8B7.22 Cn_cn09199 Ro_RO3T_16577 |
HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins |
16 | 1 | CI |
YML065W ORC1 |
576 568 524 469 481 466 464 437 - |
deldamvtksQDIMYNFFnwttyenakl deldalvsksQDVMYNFFnwatysnakl defdqiatkkQNVMYNFFnwptystskl deldqlvtlnQSVMYNFFnwptlphskl deldqlvtknQSVMYNFFnwpalrhsrl deldqlvtknQGVMYNFFnwpglrhsrl deldqlvthnQKVLYNFFnwpslphsrl deldqlltskqdvvynffnwptmrdsql ............................ |
Sc_YML065W Kl_KLLA0B05016g Ca_CAL0001320 Yl_YALI0D10104g Af_AFUA_1G10720.t1 Nc_NCUT_02320 Sp_SPBC29A10.15 Cn_cn05348 Ro |
Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity |
17 | 1 | CI |
YNR064C YNR064C |
206 207 - 256 190 - - - - |
liqrtgqtdiQLRLFFDYqnniklypaf llqrpgqtdiQLKLFHDYqnnltiypai ............................ tiapmfplyksrklaydiderdfltkgr efsrtg---irgplnwyrtrevnhkeel ............................ ............................ ............................ ............................ |
Sc_YNR064C Kl_KLLA0A10395g Ca Yl_YALI0C23224g Af_AFUA_2G16900.t1 Nc Sp Cn Ro |
Epoxide hydrolase, member of the alpha/beta hydrolase fold family; may have a role in detoxification of epoxides |
18 | 1 | C |
YML118W NGL3 |
119 - - - - - 131 - - |
vkimtyntlaQTLIRRDFfpesgpalkw ............................ ............................ ............................ ............................ ............................ itimtynvlaqtnirrsmfphsgealkw ............................ ............................ |
Sc_YML118W Kl Ca Yl Af Nc Sp_SPBC9B6.11c Cn Ro |
Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p |
19 | 1 | C |
YOR298W MUM3 |
106 73 63 - - - - - - |
lkiiptldkvleaieiwfqlhlvemtfe --gimktekiqtmvniwinefiiwsvlr -----sanlirnkcgyffwdfslylmhl ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YOR298W Kl_KLLA0F25058g Ca_CAL0000020 Yl Af Nc Sp Cn Ro |
Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases |
20 | 1 | C |
YHR064C SSZ1 |
382 382 380 380 394 393 408 - 381 |
nelaasgaalQARLISDYdadelaealq nelaasgaatqaqllsaydadelaqsle selvalgaalqaslvesfdeseikeslq aelvargaaiQAALVADFdeseiadstq selaprgaaiqasliqefdkedieqnih selnargaalqasliqeyeaedidqsth seltaigsgvQASLIGHFdaadiaastd ............................ devvargcaiqgaliagfekedvdaath |
Sc_YHR064C Kl_KLLA0C14652g Ca_CAL0001942 Yl_YALI0B12474g Af_AFUA_2G02320.t1 Nc_NCUT_00695 Sp_SPAC57A7.12 Cn Ro_RO3T_05453 |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP |
21 | 1 | C |
YDR335W MSN5 |
55 55 59 56 61 64 65 - - |
----------tnsilkyfglglldhavk ----------QNSILKHFglgllvnalk n--------gdnyivryfglsllqqsit ---------gyspvvrhfglgliqhaiq ----------naplvryfgltlldhvlr ----------qepvvrhyglslleyavk qafsslgckldihivqhfslslfetsvg ............................ ............................ |
Sc_YDR335W Kl_KLLA0F21648g Ca_CAL0003494 Yl_YALI0D04444g Af_AFUA_3G08780.t1 Nc_NCUT_03228 Sp_SPAC328.01c Cn Ro |
Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP |
21 | 2 | C |
YDR335W MSN5 |
473 472 516 502 479 353 482 - - |
veldltydwlnnrlnnyfsspfgqqvls vqldfaydwlcerlnkyfgsqfgqqvls kdpenglawlenrlqvffsselggkcin qnpvdsitwlQQRMAQFFsqenvawqvf krpqdaiphilagvdanldnlyngvepf lrltdafqyilsqaenalqtlyegqppl itpieslnwiqnrfqstvlgnmediqsq ............................ ............................ |
Sc_YDR335W Kl_KLLA0F21648g Ca_CAL0003494 Yl_YALI0D04444g Af_AFUA_3G08780.t1 Nc_NCUT_03228 Sp_SPAC328.01c Cn Ro |
Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP |
22 | 1 | C |
YDR179W-A YDR179W-A |
165 140 306 134 - - - - - |
-----cllsshlkalndssqnndlvyeq -----lfvetqvkimr-rvlqeqllldd klntfdfdkstlqvtndylksnhiifen ------slseglrvfr---phraisgvp ............................ ............................ ............................ ............................ ............................ |
Sc_YDR179W-A Kl_KLLA0D18161g Ca_CAL0001334 Yl_YALI0A14740g Af Nc Sp Cn Ro |
Putative protein of unknown function |
23 | 1 | CI |
YOR122C PFY1 |
94 94 94 94 105 101 95 95 94 |
aegvvcvrtkQTVIIAHYpptvqageat aegivivrtkQTILIGHYppgvqageat aegvicvrtkQTILIAHYpsgvqpgeat qsgiiavrtgQAIIVGHYpegvqpgeat kegivvvkavscvmvahhgeavqttnaa ktgviivkttQAILVAHYgenavagnst kegiicvatklcilvshypettlpgeaa ergvfviptnqailvaeydaptsagean adgicivkttqaflvctykegiqpgnca |
Sc_YOR122C Kl_KLLA0E02289g Ca_CAL0001759 Yl_YALI0B07183g Af_AFUA_4G03050.t1 Nc_NCUT_06062 Sp_SPAC4A8.15c Cn_cn01556 Ro_RO3T_10633 |
Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol |
24 | 1 | CI |
YIL096C YIL096C |
196 189 211 230 247 226 162 192 164 |
kdqernirehQDLIFNFFqnslqlfn-- kdqgrnihehqqlvykyfdsckqlfr-- kdvdrnirdhQRLMLSFFencqqlfd-- kdqdrnvlrnQQMLHAFFkcaipllkng tdvnrqvrsnQELLVAFFkscvpllsar tdvnrqvrynQELLVDFFkrsllslapg kdqdrnildnQKMLLAFFkaskfllse- tdqdrniltnQHMLLKFFrsvepllteg kdqdrnvianQKLLNGFFeaaapllt-- |
Sc_YIL096C Kl_KLLA0E08515g Ca_CAL0004722 Yl_YALI0E30019g Af_AFUA_5G05730.t1 Nc_NCUT_08981 Sp_SPCC1919.13c Cn_cn08174 Ro_RO3T_09555 |
Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit |
25 | 1 | CI |
YBR073W RDH54 |
471 477 369 494 457 - - 485 - |
rkllltgtpiQNDLNEFFtiidfinpgi kkivlsgtpiQNDLEEFYtiidfinpgi kkivltgtpiqnelvefhtlisflnpgv rkiilsgtpiQNDLKEFFvmvdflnpgl kriilsgtpiQNDLKEFFaavdlvnpgi ............................ ............................ rrir---tpvqndlgeywamvnfacpgv ............................ |
Sc_YBR073W Kl_KLLA0F11814g Ca_CAL0004359 Yl_YALI0E24431g Af_AFUA_1G15120.t1 Nc Sp Cn_cn03333 Ro |
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference |
26 | 1 | C |
YOL055C THI20 |
370 - 354 333 328 329 360 376 322 |
adgtlerkkfQFFIEQDYaylvdyarvh ............................ aennlpfnkflyflkqdyhylvnyaqvh akgdlkpecyyyflqqdylylrhyaraa gsgklpverfkqylvqdylylvhfarsn gdgtlpresfkgylmqdyvylihyaran akgtlplpafQDYLKQDYlylvnfaray gkgtlprkcfehyikqdyhylkhyarah adgtlptesfiyylkqdylylqhyaraa |
Sc_YOL055C Kl Ca_CAL0002907 Yl_YALI0E04224g Af_AFUA_2G10740.t1 Nc_NCUT_07500 Sp_SPBP8B7.18c Cn_cn07463 Ro_RO3T_17111 |
Multifunctional protein with both hydroxymethylpyrimidine kinase and thiaminase activities; involved in thiamine biosynthesis and also in thiamine degradation; member of a gene family with THI21 and THI22; functionally redundant with Thi21p |
27 | 1 | CI |
YGL150C INO80 |
587 629 549 572 703 992 737 745 439 |
qakklnflltQTELYSHFigrkiktnel aakklnflltQTELYSHFigskiktnel qsrklnflitQTELYSHFigkkiktdel qarklnflltQTELYSHFigrkiktdem qkrklnflisQTELYSHFigrkikgaga qkrklnflisQTELYSHFigkkiktnev qarkldflitQTELYSHFvgrkmdr--- qsrklnflltQTELYSHFigkkiktkea qarklnflitQTELYSHFigrkikqdte |
Sc_YGL150C Kl_KLLA0E08999g Ca_CAL0000831 Yl_YALI0E09012g Af_AFUA_5G06260.t1 Nc_NCUT_08856 Sp_SPAC29B12.01 Cn_cn04039 Ro_RO3T_11985 |
ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases |
27 | 2 | C |
YGL150C INO80 |
780 820 746 771 907 1192 916 945 646 |
wvneiskflpqfkilpywgnandrkvlr wvneisrfvpqfkilpywgnandrktlr wqqeitkfvpefkvlpywgnakdrkilr wqqeiskfvpdfkvlpywgngkdrkilr wqqeitkfvpdikvlpywgsakdrkvlr wqqeitkfvpqfkvlpyw---------- wqqeitrfvpklkcipywgstkdrkilr wqqelarfvprlkalpywgspkdretlr wqqeftkfvpqfralpywgnpkdrktlr |
Sc_YGL150C Kl_KLLA0E08999g Ca_CAL0000831 Yl_YALI0E09012g Af_AFUA_5G06260.t1 Nc_NCUT_08856 Sp_SPAC29B12.01 Cn_cn04039 Ro_RO3T_11985 |
ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases |
28 | 1 | C |
YIL068C SEC6 |
171 171 173 177 176 168 152 172 173 |
makea-tedaqrtvmklfsrlsgiiskf lasis-sidvqttmskvfqrvpgciekf ystrl-sddlqsivykvvspikttiklf haekasedtrr-ttikhfapldpliakf qirkaqdpsseaaltdyfqgldsvidwf qiqrgddpglqstledyfsrldkyiewf qaslegqsdlpitlensfsnlntlsdnf eakks-npqdretlvkwfekvdkvaadf qards-phdvlitlktyfrrvdvlsddf |
Sc_YIL068C Kl_KLLA0C07843g Ca_CAL0005292 Yl_YALI0D08492g Af_AFUA_4G10490.t1 Nc_NCUT_02519 Sp_SPCC1235.10c Cn_cn11101 Ro_RO3T_08395 |
Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly |
29 | 1 | C |
YCR011C ADP1 |
27 25 27 - 27 24 - 27 0 |
llscsvvlakq-dktpffegts------ wlvayvsseiigqetsfrpgtl------ qltmglkvennqdleatftrikrslvhq ............................ slsastisarsn--ysqsellp------ --lscvasayqn--ytsidmlr------ ............................ sliaagpsastdrlppphgdvp------ ---------------------------- |
Sc_YCR011C Kl_KLLA0D04554g Ca_CAL0005745 Yl Af_AFUA_6G07280.t1 Nc_NCUT_02153 Sp Cn_cn06005 Ro_RO3T_02428 |
Putative ATP-dependent permease of the ABC transporter family of proteins |
29 | 2 | CI |
YCR011C ADP1 |
824 797 814 - 864 854 - 893 488 |
ynvsndisgfQNRMGLFFfiltyfgfvt ynvendisgfQNRLGLFFfiltyfgflt ydvsndisgfQNRLGLFFfllaffgfsa ............................ ygltddikgfQNRLGLFFfilalfgfst ygltldiagfQNRLGLFFfvlalfgfst ............................ yqvtndipgfqnrlglflfilslfgfsc yrvsntiagfQNRMGLFFfyeallgfmc |
Sc_YCR011C Kl_KLLA0D04554g Ca_CAL0005745 Yl Af_AFUA_6G07280.t1 Nc_NCUT_02153 Sp Cn_cn06005 Ro_RO3T_02428 |
Putative ATP-dependent permease of the ABC transporter family of proteins |
30 | 1 | C |
YNL262W POL2 |
1193 1170 1191 1190 1188 1196 1178 1221 1186 |
kiatkedkfkQTSLTKFFsktknvpt-- kiavsedkfkQTSLNRFFkstkapp--- kvknsedimqQKSISNFFkkttked--- iikqrdnpikqstlssyfvkgklptpep rinmkedkfkqtkmtdmfgkteknpls- rinikddkmkqkkltdlfgpttkgplq- rvavlnskyqqkkidsifslaptn---- riatkedkfqqhkitdmft--------- rvaikndpqrqylitdifsraek----- |
Sc_YNL262W Kl_KLLA0C02585g Ca_CAL0000768 Yl_YALI0E26367g Af_AFUA_3G09560.t1 Nc_NCUT_05475 Sp_SPBC25H2.13c Cn_cn11213 Ro_RO3T_00774 |
Catalytic subunit of DNA polymerase (II) epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair |
30 | 2 | C |
YNL262W POL2 |
1682 1652 1673 1666 1681 1692 1650 1673 1684 |
idvlyarklkkenivlwwnekaplpdhg idlmyarqlkknnivlwwndksplpdhg vdieyarrlsennivlwwspn-plpdlg idvsyarrliqnsvvlwwsaa---lstg idisyarrlqqnnvvlwwsng-prpdha idiayarrlmannvvlwwsps-prpdha idvvysrklkehniilwwnkg-ptpdlg adiefarrlkqqdmliwwsst-prpdlg sdvifartmiqndmiiwwstt-klpdlg |
Sc_YNL262W Kl_KLLA0C02585g Ca_CAL0000768 Yl_YALI0E26367g Af_AFUA_3G09560.t1 Nc_NCUT_05475 Sp_SPBC25H2.13c Cn_cn11213 Ro_RO3T_00774 |
Catalytic subunit of DNA polymerase (II) epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair |
31 | 1 | C |
YPR018W RLF2 |
227 221 193 139 241 232 177 348 - |
rlkeeakeraQSRIGNFFkkls------ rkkeetkersQSRIGNFFkkat------ rkieeakersQMKISSFFqigqkrkekk kkkeqeqtriMSFFNKKTkkkt------ vkpkppaqptddtasdspkipiadg--- kinpatpkekpvavkveskdvemt---- nkerqqlklnNFFTKGVEkriapne--- kkkeeamakqakamsmffkpkptciakk ............................ |
Sc_YPR018W Kl_KLLA0D02090g Ca_CAL0004223 Yl_YALI0F21637g Af_AFUA_5G03720.t1 Nc_NCUT_03891 Sp_SPBC29A10.03c Cn_cn03648 Ro |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin |
32 | 1 | C |
YNL279W PRM1 |
661 643 589 643 676 693 646 726 526 |
---------------------------- ---------------------------- aissphelseqekqvygyplshplidgk dinvprvlppqitipkpalfmrnhipsp tntdarsmpppapapryeaststvvasr mvgnpasphyqnekfgggggmhdvaspa hvydfqnfqyeeddcidykrslglisls aekqfrgttptnclesythadvpnvnng ---------------------------- |
Sc_YNL279W Kl_KLLA0C01936g Ca_CAL0001069 Yl_YALI0E08580g Af_AFUA_4G11210.t1 Nc_NCUT_09096 Sp_SPAP7G5.03 Cn_cn06368 Ro_RO3T_13695 |
Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p |
33 | 1 | C |
YJL002C OST1 |
434 419 430 417 461 457 414 437 418 |
rnlisqvangQVLIKYDYpkssffkkpl knlneelkdapvflkyrysksellrkpa knlfddlhkldvfvkykytkinfvykiv vnfvdqhrggivflkytlpgsaatikpi enlsdeardsqivvtydhsfwdglrkpf rnlvddfrdrdltvtydypmsavlrkpl lnvtdgvpsdivhisyeynssafflria arctedhakt-vyvtysypfsalmqkpl k---nvirnhelpiqvtlsrkqrylvpn |
Sc_YJL002C Kl_KLLA0F12980g Ca_CAL0000404 Yl_YALI0F14795g Af_AFUA_2G05790.t1 Nc_NCUT_02156 Sp_SPAC27F1.07 Cn_cn10203 Ro_RO3T_17194 |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins |
34 | 1 | C |
YJL047C RTT101 |
268 248 - - - - - - - |
ieglspkdfymktlrqyyceesnlrprl sdhfkrvdslqkqi-iyycseyqilcqn ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YJL047C Kl_KLLA0F02145g Ca Yl Af Nc Sp Cn Ro |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p |
35 | 1 | C |
YDL229W SSB1 |
350 - - - - - - - 349 |
vggstripkvQKLLSDFFdgkqleksin ............................ ............................ ............................ ............................ ............................ ............................ ............................ vggstripkiqsllqdvfggkelnksin |
Sc_YDL229W Kl Ca Yl Af Nc Sp Cn Ro_RO3T_10928 |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in folding of newly-made polypeptide chains; member of the HSP70 family; interacts with phosphatase subunit Reg1p |
36 | 1 | C |
YNL163C RIA1 |
263 263 259 263 286 281 249 268 275 |
qklgakrenlQKVLWGDFymdpktkkii eklgakrenlQKVLWGDFymdpktkkii kklgfsqqalsktlwgdfyldmknkkii aklgmkrenlQKCLWGDFyfdpktksvi rklgikrsilekvlwgdfyldpktkrvl kklgikrgllekvlwgnfymdpktkkvl kklglkqkaltkclwgdyyldpktkrvl eklkikegnlrrvlwgdwyldpktkrvv kklgfkeqvlqkclwgeyyfdpkakrvl |
Sc_YNL163C Kl_KLLA0D07898g Ca_CAL0001869 Yl_YALI0D16291g Af_AFUA_5G13520.t1 Nc_NCUT_05939 Sp_SPCC553.08c Cn_cn01036 Ro_RO3T_01367 |
Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p) |
37 | 1 | CI |
YLL018C DPS1 |
307 305 328 314 300 339 313 315 302 |
ylaqspqfnkQQLIVADFervyeigpvf ylaqspqlykQQLIAADFervfevapvf flaqspqlykQQLIAADFekvfeiapvf flaqspqlykQMLMSGDFervfeiapvf ylaqspqlykqmciagdmesvfeiapvf flaqspqfykqfeiaggrkrvfsigpvf flsqspqlykqmliaadrervfeigpvf flaqspqlakqmaiagdmervyeiapvf flaqspqlykQMCIAADFgkvfeiapvf |
Sc_YLL018C Kl_KLLA0D03839g Ca_CAL0001457 Yl_YALI0D22264g Af_AFUA_2G02590.t1 Nc_NCUT_00923 Sp_SPCC1223.07c Cn_cn04013 Ro_RO3T_04618 |
Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation |
38 | 1 | CI |
YGL197W MDS3 |
74 73 - - - 161 - - 32 |
nlpvvnsmqlQKELILFFakeknngssf nlqeitstnlQQELIMHFarerkdsnrf ............................ ............................ ............................ pftqppletivnaeedwmdnnrmspmds ............................ ............................ plvgasttvvgnqlflfggrlvssrq-- |
Sc_YGL197W Kl_KLLA0F12452g Ca Yl Af Nc_NCUT_05312 Sp Cn Ro_RO3T_15114 |
Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions |
39 | 1 | C |
YLR263W RED1 |
353 349 - - - - - - - |
vnnipkisevQNFLVLDYieeepenege atklpkisevqtyislrfp--ssyddgi ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YLR263W Kl_KLLA0F20405g Ca Yl Af Nc Sp Cn Ro |
Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity |
40 | 1 | C |
YGL173C KEM1 |
542 542 547 538 540 503 527 553 1032 |
dlakdyveglqwvlyyyyrgcpswswyy emtenyvgglqwvlyyyyrgcpswswyy emtkhyieglqwvlyyyyrgcpswnwyy altenyveglqwilhyyydgvpswswyy kltenyvqglqwvlyyyyrgiaswpwff kltenyvqglqwvlyyyyrgiaswpwfy amaeryveglqwvlfyyyrgcqswgwyy dlvhhyieglqwilnyyykgvsswgwfy kligsyvigiqwvlqyyyngvaswgwfy |
Sc_YGL173C Kl_KLLA0F22385g Ca_CAL0006374 Yl_YALI0C23144g Af_AFUA_5G03120.t1 Nc_NCUT_06654 Sp_SPAC17A5.14 Cn_cn05367 Ro_RO3T_05296 |
Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance |
41 | 1 | CI |
YDR097C MSH6 |
27 26 25 6 34 30 22 9 0 |
gstssqkkmkQSSLLSFFskqvpsgtps gs-sgkkkykQATISSFFkkre---kpv nstgstk--kQSSLMDFFkpmaskdksk -----makakqqsvlsffkktpvketkk stsstqnmknQRSILGFFqkss----pl krsvlastgrQSSILGFFskaassgtpt ktkdssaktkQKTLFGFFskipnvkqek --mpsakqatLAAFFGAPkpgprpsqpr ---------------------mevdqpv |
Sc_YDR097C Kl_KLLA0C17732g Ca_CAL0006305 Yl_YALI0F26499g Af_AFUA_4G08300.t1 Nc_NCUT_08326 Sp_SPCC285.16c Cn_cn11096 Ro_RO3T_11159 |
Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p |
42 | 1 | C |
YGL224C SDT1 |
78 82 67 33 83 42 28 - 25 |
-sstrihdlmQQSILRFFqthlklsped -kslrihdlmeqsihqyfqmkfnldnet -rstrifemmqvkihdyfkkslslnded -kdkgvdalmgerinnyfqtklgldkeh tadcnihdemQKLIHQFFvkhlslsaed -ksakvhdlmadlidqyfarhlnlpwed -ksykihnmmaaritaffsdklgiptee ............................ -knlkihtlmkekireyfvkevgvpeee |
Sc_YGL224C Kl_KLLA0A01408g Ca_CAL0002898 Yl_YALI0F26785g Af_AFUA_2G13470.t1 Nc_NCUT_05029 Sp_SPAC24B11.05 Cn Ro_RO3T_10469 |
Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives |
43 | 1 | CI |
YMR216C SKY1 |
276 241 374 163 232 162 - 244 88 |
pliyvkqiskQLLLGLDYmhrrcgiiht pivyvkqiakQLLLGLDYmhrkcgviht pvvfvkqiakqllsaldflhrqcgviht pvklvkqitkQVLLGLDYlhrecgivht pmplvkqitkQVLLGLDYlhrecgiiht pmalvkqitkQVLLGLDYlhrecgiiht ............................ pqhivkqiakQVLLGLDYlhrecriiht ptkivkqiskQALLGLDYlhrkcgiiht |
Sc_YMR216C Kl_KLLA0C07216g Ca_CAL0001525 Yl_YALI0A18590g Af_AFUA_4G03140.t1 Nc_NCUT_08871 Sp Cn_cn05512 Ro_RO3T_00053 |
SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1 |
44 | 1 | C |
YMR201C RAD14 |
115 112 162 55 66 146 55 90 - |
-----psirkQDYIEYDFatmqnlnggy -----psvrrQDYIEYDFstmknsyggf kkfqpppirkQDYIEFDFatmkdtkggf -amgappitrasyieydlanmkdtqggy ------arnfakyveydfskmtdtkggf gslppisrkftkyvdynfsamtdtkggf -tfdeqseitKDYIEYDFskiedtkggy ----dpslgk--yfeydlskmrnsrggf ............................ |
Sc_YMR201C Kl_KLLA0F06424g Ca_CAL0003083 Yl_YALI0B01474g Af_AFUA_5G01800.t1 Nc_NCUT_08618 Sp_SPBC649.03 Cn_cn07342 Ro |
Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein |
45 | 1 | CI |
YCR092C MSH3 |
4 3 7 0 10 7 0 8 0 |
-------magQPTISRFFkkavkselth --------myQPTISHFFkssqpssqtd ----mssqkrQSTLSRFFttikpsqste ---------------MKRskqatlsrff -mtlsssqssPPSTQNLKrkqqtissff ----magpsrLP-----Dkkqasissff ---------------------mrgmsyn ---mpsegsqQPSLDSFFkrknprvepy ---------------------------- |
Sc_YCR092C Kl_KLLA0C18590g Ca_CAL0000288 Yl_YALI0A09724g Af_AFUA_7G04480.t1 Nc_NCUT_09634 Sp_SPAC8F11.03 Cn_cn03578 Ro_RO3T_06461 |
Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability |
46 | 1 | CI |
YHR031C RRM3 |
368 344 - - - 552 - - - |
rknddpfggiQLVLTGDFfqlppvakkd lnrtkpfggiqlvftgdffqlppvpdrd ............................ ............................ ............................ rnngrpwggiQLVITGDFfqlppvldkd ............................ ............................ ............................ |
Sc_YHR031C Kl_KLLA0D13354g Ca Yl Af Nc_NCUT_00436 Sp Cn Ro |
DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p |
47 | 1 | C |
YPL258C THI21 |
370 371 - - - - - - - |
adgslepkkfQFFIEQDYlylvnyaris sngtmnmerfhkylkqdynylqvfarih ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YPL258C Kl_KLLA0B13926g Ca Yl Af Nc Sp Cn Ro |
Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p |
48 | 1 | C |
YDL145C COP1 |
1134 1142 1154 1178 1142 1156 1140 1155 1172 |
kiknkadsmasdaipidfdpyakfdica kikakadsmaydaieidfdpyaefdica klknkadtiandtieinfdpfaefdicc kvkhradaqpldaieldfdvtanfaicp kikaqcerspqdkidiefdqfaefdica rtkaqcernphdaveiefdqfaefeica raitlgdrnphdafeieydphvemricp avisrgqrnprdvheiaydqnasfnica kiqgvcertlqdeltlnydqynpfdvca |
Sc_YDL145C Kl_KLLA0F04884g Ca_CAL0000105 Yl_YALI0E19767g Af_AFUA_3G08840.t1 Nc_NCUT_03188 Sp_SPBPJ4664.04 Cn_cn07432 Ro_RO3T_05486 |
Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway |
49 | 1 | CI |
YJR043C POL32 |
338 377 - - - - - - - |
tpssnkrlkkQGTLESFFkrkak----- pvekkkarssQRTLESFFgkkkg----- ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YJR043C Kl_KLLA0E22419g Ca Yl Af Nc Sp Cn Ro |
Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p |
50 | 1 | C |
YCR032W BPH1 |
1931 1782 2025 1948 2279 - - - - |
ldifkkthmaqitsfaywklgefitgdk ---vkhahsskitvlsnfdqsliatgds dtlflsvhssdittvlqlghklfvtgae vtvfeglhlspielvvalenmlvltadr lghfehlhigqlsctifadsrtlvtsgt ............................ ............................ ............................ ............................ |
Sc_YCR032W Kl_KLLA0B07667g Ca_CAL0000533 Yl_YALI0E04312g Af_AFUA_5G09220.t1 Nc Sp Cn Ro |
PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting |
51 | 1 | CI |
YER166W DNF1 |
1154 1196 1267 1217 1095 1102 1036 1159 1012 |
gigiageegrQAVMCSDYaigqfrylar gvgiageegrQAVMSSDYaigqfryltr gvgiageegrQAVMSSDYaigqfrylar gvgiageegrQAVMCSDYaigqfrfldr gvgivgeegrQAAMSSDYaigqfrflqr gvgiageegrQAVMSSDYaigqfrfltr gvgivgeegraaamsadyaigqfrflsk gvglyglegsQAAMSADYafgqfrfltr gigisgvegrQAVMASDYaiaqfrflrk |
Sc_YER166W Kl_KLLA0C17644g Ca_CAL0003657 Yl_YALI0C00495g Af_AFUA_6G02070.t1 Nc_NCUT_07441 Sp_SPAC24B11.12c Cn_cn04235 Ro_RO3T_07539 |
Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase |
51 | 2 | C |
YER166W DNF1 |
1280 1322 1393 1343 1221 1228 1162 1285 1138 |
flwymldglyQSIICFFFpylvyhknmi fwlymfdamyqsvicfflpylcyyktgi fylycldgiyQSAISYFFpylly-mvaf fveytvdglyqslvcfffpflmfyntas fwlymldgfyqsiicfympyllfspatf fwaymadgiyqsvmsffipfifciltpa figymldgfyQSVICFFFsflvinnvtt fwlymfdglyqsaviffipyfaygtges fwltivdsiyqssvcfffpymllvggai |
Sc_YER166W Kl_KLLA0C17644g Ca_CAL0003657 Yl_YALI0C00495g Af_AFUA_6G02070.t1 Nc_NCUT_07441 Sp_SPAC24B11.12c Cn_cn04235 Ro_RO3T_07539 |
Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase |
52 | 1 | CI |
YDR334W SWR1 |
957 1026 1097 1165 1089 1201 704 653 837 |
hivycklskrQRFLYDDFmsraqtkatl hiiycrlskrQRFLYDDFmsraqtketl hivycrlskrQRFLYDDFmsraktketl hvvycrlskrQRYLYDDFmsraqtretl hvvycrlskrqrflydgfmsmaqtketl hvefcrlskrqrelydgflsradtretl hvvycqlskrQRFLYDDFinrartreil hvvycrlskrqrflydefmsrastheal hviycklskrQRYLYDDFmgraktketl |
Sc_YDR334W Kl_KLLA0F21758g Ca_CAL0001763 Yl_YALI0D04961g Af_AFUA_7G02370.t1 Nc_NCUT_09773 Sp_SPAC11E3.01c Cn_cn09225 Ro_RO3T_06478 |
Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A |
53 | 1 | CI |
YIL048W NEO1 |
906 903 921 779 1038 1092 794 866 740 |
gvgivgkegkQASLAADFsitqfchlte gvgivgkegkQASLAADFsitqfchltk gvgivgkegkQASLAADFsidqfcylsk gvgivgkegrQASLAADFsitqfchltk gigivgkegrQASLAADFsithfhhltk gvgivgkegrQASLAADFsieqfhhltk gigivgkegqQASLAADYsvkefshvsr gvgivgkegkQASLAADFsinqfsyltk gvgivgkegkQASLAADFsitqfshltr |
Sc_YIL048W Kl_KLLA0C08393g Ca_CAL0001981 Yl_YALI0F01122g Af_AFUA_6G03950.t1 Nc_NCUT_03502 Sp_SPAC6C3.06c Cn_cn09332 Ro_RO3T_14574 |
Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus |
54 | 1 | CI |
YKL113C RAD27 |
340 340 340 352 341 344 338 407 459 |
rlkkglksgiQGRLDGFFqvvpktk-eq rlrkglkvgvQKRLDSFFkiqpktk-ee klkkglkggvQGRLDGFFkvvktdd-kk rlmkqvkvkpQARLDGFFkvmpkeggek rlqknlktaqQSRLEGFFkpvartdeek kleknmktsqQARIEGFFkilpkteeek rlekasktipQGRLDSFFkpvpsspkkp klskmlaakqQGRLDGFFtvkpkepaak klaknlkqatqtrvqdffktipsttpkk |
Sc_YKL113C Kl_KLLA0F02992g Ca_CAL0000208 Yl_YALI0F20042g Af_AFUA_3G06060.t1 Nc_NCUT_03122 Sp_SPAC3G6.06c Cn_cn04517 Ro_RO3T_02488 |
5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family |
55 | 1 | CI |
YGR135W PRE9 |
173 173 172 173 172 172 172 189 172 |
isvgantsaaQTLLQMDYkddmkvddai isvgantqaaQTLLQMDYkdditldgai tsigannsaaQTLLKKDYkddltlkdac tsmgankasaQTLLRQDYkddmtlaeac tsvgannasaQSLLKQDYkedcdlkeac tsagannasaQSLLKQDYkedctlkeac nsiggnstsvqslmrqeykddinldeas tsiganhssatsllkqdykedlsledak tcigannataqsilkqdhkedmtleeak |
Sc_YGR135W Kl_KLLA0E03917g Ca_CAL0004819 Yl_YALI0C19382g Af_AFUA_6G08960.t1 Nc_NCUT_01423 Sp_SPAC13C5.01c Cn_cn06287 Ro_RO3T_16333 |
Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform |
56 | 1 | CI |
YDL106C PHO2 |
365 337 296 480 - - 542 - 303 |
--------nnQWSICDDFsegrqvndaf --------snQWSICEDFsegrqvndaf ----------QWSICDDFsegqqvscaf --------krhrsnssasfdrrsstsat ............................ ............................ ppvfhmitsegqgnctdftegnqasevl ............................ --------patineedeedeekepkdly |
Sc_YDL106C Kl_KLLA0D10043g Ca_CAL0004635 Yl_YALI0F16852g Af Nc Sp_SPAC32A11.03c Cn Ro_RO3T_10318 |
Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p |
57 | 1 | C |
YDL164C CDC9 |
0 0 0 0 7 6 0 0 0 |
---------------------------- ---------------------------- ---------------------------- ---------------------------- ----mtilrisasiapvshycrgpvaft -----mppkqQQTLGKFFgkadapaggk ---------------------------- ---------------------------- ---------------------------- |
Sc_YDL164C Kl_KLLA0D12496g Ca_CAL0006047 Yl_YALI0F01034g Af_AFUA_2G09010.t1 Nc_NCUT_06250 Sp_SPAC20G8.01 Cn_cn08403 Ro_RO3T_07347 |
DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination |
57 | 2 | C |
YDL164C CDC9 |
22 22 28 20 78 75 24 14 7 |
sarplksrlpllmssslp--------ss vqrpvtfkvpsqqms------------- qanrimsnkkQQSLARFFggitppsgsn rvmflsfrtpttrrvvfn---------- ptmadskgrkQATLGRFFgs----naeg veemkikdkspaktgrgrgr----pakg vnqyirmstrQSDISNFFis----sash ieypvksnirkkrtvilsdd----edeg ----mssnkkQAKLNAFFg--------- |
Sc_YDL164C Kl_KLLA0D12496g Ca_CAL0006047 Yl_YALI0F01034g Af_AFUA_2G09010.t1 Nc_NCUT_06250 Sp_SPAC20G8.01 Cn_cn08403 Ro_RO3T_07347 |
DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination |
57 | 3 | C |
YDL164C CDC9 |
38 32 52 31 98 94 44 34 21 |
--ssagkkpkQATLARFFtsmknkpte- -----tkrskqltldgflrpnk------ sgsnstspekQQSLTRFFgsssnnss-- -------makQQTLN-FFgtkrkas--- naegpktapkkqttlsfsskkdkksdvv pakg-kevakevakekssaeede--dvm sashksehvevsq-sssdsknvd----- edeglgpsvikeqvsspkhshls----- -----gdkvkkqqklksvdpdae----- |
Sc_YDL164C Kl_KLLA0D12496g Ca_CAL0006047 Yl_YALI0F01034g Af_AFUA_2G09010.t1 Nc_NCUT_06250 Sp_SPAC20G8.01 Cn_cn08403 Ro_RO3T_07347 |
DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination |
58 | 1 | C |
YIR023W DAL81 |
286 464 290 356 232 199 - - 108 |
lslrkvsptaQFILQDDFdttlhskqey valrkvspnaQFILRDDFnqelylkqer vslrkvsdtvqfilkedqspqsyqtmsn tamrrvapdvlftirndfaddlhsefia rvrkigndgtfmrvveppsqadspsisl tlrkvgdedtflmlp------------- ............................ ............................ tdtikglndwiykvsg------------ |
Sc_YIR023W Kl_KLLA0E18195g Ca_CAL0003338 Yl_YALI0D02783g Af_AFUA_3G08050.t1 Nc_NCUT_01365 Sp Cn Ro_RO3T_03487 |
Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism |
58 | 2 | C |
YIR023W DAL81 |
588 757 590 624 500 452 - - 378 |
--vlklakplqlklrewyhslpknlsms --vlklakplqlklrewyhslphklsms --vlklakplqlrlrdwfrslpielqms --iltkakpiqiklrdwhiglpeclrms rmilerakpaqirlkewfaslppqlkmd qlvlslakpiqlklkewysglpdsvrmd ............................ ............................ ---davvayldkalsewksalppslqfs |
Sc_YIR023W Kl_KLLA0E18195g Ca_CAL0003338 Yl_YALI0D02783g Af_AFUA_3G08050.t1 Nc_NCUT_01365 Sp Cn Ro_RO3T_03487 |
Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism |
58 | 3 | C |
YIR023W DAL81 |
669 838 677 705 588 578 - - 482 |
aiefird-lknehinafwyncstgnlml aiefird-lktehinsfwytsstgnlal siefvrd-lkqehihsfwhcsatsnftl aielvdt-lkhehiqafwhssaatnfal amdfvnr-lrqphlrsfwpaasrtnfsl amdfvnr-ltpshlrafwyfasktnfal ............................ ............................ swnfviypvftaslihiynatqsdnqta |
Sc_YIR023W Kl_KLLA0E18195g Ca_CAL0003338 Yl_YALI0D02783g Af_AFUA_3G08050.t1 Nc_NCUT_01365 Sp Cn Ro_RO3T_03487 |
Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism |
59 | 1 | C |
YOR016C ERP4 |
191 - - - - - - - 174 |
mgvmvgisivQALIIQFFftsrqknyv- ............................ ............................ ............................ ............................ ............................ ............................ ............................ siaiisiaalqtlvvkgffnvkkggv-- |
Sc_YOR016C Kl Ca Yl Af Nc Sp Cn Ro_RO3T_00105 |
Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport |
60 | 1 | CI |
YDL051W LHP1 |
144 134 124 268 228 191 169 172 122 |
--------elQENLEAFFkk-lgeinqv --------elQEELEKFFng-fttvnqv --------wvnekvivqlpkekevcsir pltreeelalQIEIEKFFeg-ygkivqv --------ttQIDIEAFFap-ygpvnai --------stQFDIEAFFtk-fgqvnlv ----------QIALEKFFeenagpisav ---------tqekieaycdq-fgkinav -----klielQDKIDDFFne-kakvlct |
Sc_YDL051W Kl_KLLA0E01277g Ca_CAL0004304 Yl_YALI0E18854g Af_AFUA_1G12590.t1 Nc_NCUT_08417 Sp_SPAC57A10.10c Cn_cn05250 Ro_RO3T_11302 |
RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen |
61 | 1 | C |
YGL228W SHE10 |
272 313 - - - - - - - |
egstdvnvneQALLQEDFdmwsetilqk d---ecdmsmeemlrndfmswkitienk ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YGL228W Kl_KLLA0A01177g Ca Yl Af Nc Sp Cn Ro |
Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest |
62 | 1 | C |
YPL014W YPL014W |
46 65 - - - - - - - |
eaqhqtqdp-QPLLNCDYddmiafdr-n thphisvppsqpsidpdvemdldhdeyn ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YPL014W Kl_KLLA0F27225g Ca Yl Af Nc Sp Cn Ro |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus |
63 | 1 | C |
YLR258W GSY2 |
160 158 - - - - - - - |
flgevahldsQHAIVAHFhewlagvalp flgelahmnqtnaivahfhewlagvaip ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YLR258W Kl_KLLA0F23133g Ca Yl Af Nc Sp Cn Ro |
Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase |
64 | 1 | C |
YFL007W BLM10 |
405 404 398 264 250 263 - 333 64 |
pyhyhihskiidyfpfcys--------i pyhyhknrnvldyfsvmfs--------l pngvedendirhyiqsffy--------m ------scnpqtylpslfh--------l ppqsredllpqhylptyfh--------l apptepqsqpsdfvptffh--------l ............................ vdparsdpsllskiphgfqntpeeevtn rp--thttgpqtylptlfs--------l |
Sc_YFL007W Kl_KLLA0E12057g Ca_CAL0005443 Yl_YALI0D22520g Af_AFUA_4G11290.t1 Nc_NCUT_05521 Sp Cn_cn06468 Ro_RO3T_08855 |
Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200 |
64 | 2 | C |
YFL007W BLM10 |
1869 1876 1919 1749 1669 1672 - 1837 1457 |
ledsvvglnpQQFIKTDYfyrtstifyw erllikdlpaqdilktryfylastmfyw wrkecqhltpqeilktnyiytattvliw ----------sdinkksitntaktlvaf wrhers---pgqqtpssytsgsktvllw wrhert---pgqqtpssytsgsktvlvw ............................ lkelrphg--pkavlsdhdtsattailw wlgemg----gntassdyahasktilcw |
Sc_YFL007W Kl_KLLA0E12057g Ca_CAL0005443 Yl_YALI0D22520g Af_AFUA_4G11290.t1 Nc_NCUT_05521 Sp Cn_cn06468 Ro_RO3T_08855 |
Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200 |
65 | 1 | C |
YDR090C YDR090C |
69 69 69 71 73 73 81 70 - |
vskgnvilqvQPHLFMFFcsisfvqscy itrgniilqiQPHLFMFFcslswvqsly atdgsiplriQPQLFTFFctlswiqtly aqrggvalqvqpqifgifsfigwfqcly sahgsildspe---mltfvlqkvniplq twkatllaliv---acvfagveaalilt vqelnialkvqpelfqalafttffqcly aqnfsiplqvqpqvfaalatvswcqclh ............................ |
Sc_YDR090C Kl_KLLA0D02178g Ca_CAL0004785 Yl_YALI0C04884g Af_AFUA_5G08410.t1 Nc_NCUT_01327 Sp_SPAC2E12.03c Cn_cn02310 Ro |
Putative protein of unknown function |
66 | 1 | CI |
YLR262C YPT6 |
40 41 41 39 45 44 41 51 37 |
fmydtfddhyQATIGIDFlsk-----tm fmydtfddnyQATIGIDFlsk-----tm fmydtfdetyaatigidflsk-----tm imydkfdqnyeatigiqflsk-----pm fmydsfdntyQATIGIDFlsk-----tm fmydsfdnmyQATIGIDFlskacstptm fmydqfdntyQATIGIDFlsk-----tm fmydtfdntyQATIGIDFlsk-----tm ahykiy-----atigidflsk-----tm |
Sc_YLR262C Kl_KLLA0F20471g Ca_CAL0001741 Yl_YALI0B22154g Af_AFUA_2G15570.t1 Nc_NCUT_05002 Sp_SPAC4C5.02c Cn_cn13053 Ro_RO3T_08513 |
GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6 |
67 | 1 | C |
YIL050W PCL7 |
255 - - - 449 392 167 - 148 |
slqelnhlelQFLILCDFkllvsveemq ............................ ............................ ............................ plvelnhlelQFLLLNDFrlsisveele rvaelnmleleflhrvdwkivpdpdvlv plhelnhlelsffvfndfnlfisledlq ............................ tvtelnaleleflylndydlfvtidelq |
Sc_YIL050W Kl Ca Yl Af_AFUA_7G04640.t1 Nc_NCUT_01824 Sp_SPBC20F10.10 Cn Ro_RO3T_06770 |
Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated |
68 | 1 | C |
YDR532C YDR532C |
102 87 - - - - - - - |
mellkltyleQETLDYFFrftlss-tkp tnslkqihlelesidnflryaipsdqti ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YDR532C Kl_KLLA0C00891g Ca Yl Af Nc Sp Cn Ro |
Protein of unknown function that localizes to the nuclear side of the spindle pole body and along short spindles; deletion mutants have short telomeres; forms a complex with Spc105p |
69 | 1 | CI |
YNL209W SSB2 |
350 350 350 350 351 340 349 394 - |
vggstripkvQKLLSDFFdgkqleksin vggstripkvQKLLSDFFegkqleksin vggstripkvQKLLSDFFdgkqleksin vggstripkvQKMLSDFFdgkaleksin vggstripriQKLLSDFFdgkkleksin vggstripkvQKLLSEFFdgkkleksin vggstripkvqrlvsdffdgralnksin vggstripkiqslvseyfggrqlnksin ............................ |
Sc_YNL209W Kl_KLLA0D19041g Ca_CAL0001367 Yl_YALI0A00132g Af_AFUA_8G03930.t1 Nc_NCUT_01229 Sp_SPBC1709.05 Cn_cn01313 Ro |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1 |
70 | 1 | C |
YAL001C TFC3 |
1137 1141 1377 1373 - - 1320 - - |
seickwllerQVLITTDFdgywvnhnwy sevvkwlsntqrisaidyggytvcdgwy tavidwlkksgciekgayngystsnnwl edvmqwlcekqclrkgecdgywlmpgwy ............................ ............................ nevldyfiaagaaiek--dglylnhnyl ............................ ............................ |
Sc_YAL001C Kl_KLLA0A08734g Ca_CAL0002026 Yl_YALI0C22231g Af Nc Sp_SPBC336.07 Cn Ro |
Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding |
71 | 1 | C |
YJL170C ASG7 |
44 30 - - - - - - - |
cksckmsvpvQPWLPRFFvfgilcpvfw cgsckigknvefymvrffimgfvlpvlw ............................ ............................ ............................ ............................ ............................ ............................ ............................ |
Sc_YJL170C Kl_KLLA0A06578g Ca Yl Af Nc Sp Cn Ro |
Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell; specific to a-cells and induced by alpha-factor |
72 | 1 | C |
YIL109C SEC24 |
648 651 642 - 657 687 666 658 692 |
slaevyasadQLAIASFYnskavekaln kltevyasadqlaitayfaqkaveraps klvdiyasadqlaianyfthkaiekals ............................ nladvyasadqqaiatyfshkavervls nladvyasadqcaiatyfshkavekalg smtdlyasadqvaiaqyltvrasekals siaelytsadqialatylankaversms siselyasanqqaiaaylgvkaverglt |
Sc_YIL109C Kl_KLLA0F03729g Ca_CAL0004422 Yl Af_AFUA_6G12830.t1 Nc_NCUT_03232 Sp_SPAC22F8.08 Cn_cn02547 Ro_RO3T_09792 |
Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p |
73 | 1 | C |
YFR018C YFR018C |
77 63 - 73 73 70 - 69 - |
vpgsegsreiQRFIIEHFnn-------- vpgskgskevqefvldefk--------- ............................ vpdtdgirevqkfitdfvstqtysegev vpgtlgstavlnhfadffrt------sl vpgtpgqakvqkhfvdffsr------el ............................ psgsenntlvqnyissvfsk-------- ............................ |
Sc_YFR018C Kl_KLLA0D04576g Ca Yl_YALI0E29205g Af_AFUA_4G08280.t1 Nc_NCUT_08990 Sp Cn_cn12299 Ro |
Putative protein of unknown function |
74 | 1 | C |
YKR082W NUP133 |
628 599 551 607 500 734 594 620 - |
lsnynltqnehlttktvvinspdvfpvi lsessyqsdsdfisdgivk-----ipel vletqlgdireffthnvad-----inpv ksvdknqntdqdpvqdfftsrtleaanl fktksedyedkdnvrdwflfdtfrmehi ktepnpavgevdpvrhwfindvwrleif iyrltqsassdnalrewflhniesidql psssptdereqdlvrlffrtevsnldkl ............................ |
Sc_YKR082W Kl_KLLA0A07909g Ca_CAL0005922 Yl_YALI0A03883g Af_AFUA_4G05840.t1 Nc_NCUT_03668 Sp_SPAC1805.04 Cn_cn12020 Ro |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p |
74 | 2 | C |
YKR082W NUP133 |
829 785 717 792 738 971 812 871 - |
tldqn-dsttvslyetffnefpkefsft slp---kitafslydeffqkygydfaks ihqeetnstdqsnyskyfeeygysfasc nnnkqsesdaeyairkylhnfgydfasq nvtnyeseqlgrristyfekfgepwada eeyrakaedrkrqmggffnqyqerfafp --qlyedneltdalnnyldlfgikfafi -dpvagqgkgdsriqvyiekfgedfafe ............................ |
Sc_YKR082W Kl_KLLA0A07909g Ca_CAL0005922 Yl_YALI0A03883g Af_AFUA_4G05840.t1 Nc_NCUT_03668 Sp_SPAC1805.04 Cn_cn12020 Ro |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p |