confind (c) Finn Drablos, NTNU 2007,2012 Version 02.10.2012 Program started Fri Dec 21 13:49:03 CET 2012 ---------- Configuration file for APIM motif Version FD 02-10-2012 Datasets are from Inparanoid 7.0. Gene descriptions are taken from Inparanoid 7.0. Localisation data are from eSLDB. Using K as equivalence for KR in consensus Using F as equivalence for FYW in consensus Using L as equivalence for LVI in consensus ---------- Found 5884 sequences in ./lib/S.cerevisiae.fa Got match in 280 sequences against pattern [KR][FYW](([LVI][ALVI])|([ALVI][LVI]))[KR] Removed 0 entries with no info in ./ref/eSLDB_Saccharomyces_cerevisiae_TS.txt matching .* There are 280 entries left Found 195 orthologs in Kl (Kluyveromyces lactis) Found 183 orthologs in Ca (Candida albicans) Found 168 orthologs in Yl (Yarrowia lipolytica) Found 155 orthologs in Af (Aspergillus fumigatus) Found 140 orthologs in Nc (Neurospora crassa) Found 143 orthologs in Sp (Schizosaccharomyces pombe) Found 123 orthologs in Cn (Cryptococcus neoformans) Found 114 orthologs in Ro (Rhizopus oryzae) Removed 60 entries without orthologs There are 220 entries left Created 69 new sequence files Added 355 new orthologs to these sequence files Ran ClustalW on 69 library files Removed 136 sequences where pattern was not conserved There are 84 entries left Missing information on gene for 0 proteins Removed 0 duplicate sequences representing the same gene There are 84 entries left Description is missing for 0 genes ---------- Pro - Protein number (green if on priority list) # - Motif number i protein CI - Entry is accepted according to Consensus or Individual pattern hits Protein ID / Gene ID - IDs from input data Pos - Position of motif in sequence Alignment - Alignment of motif (UPPER case) and flanking region (lower case) lower case only - no hit by motif, "-----" - gaps, "....." - missing protein Ortho ID - ID of Orthologs, with organism code (see above) Description
Pro | # | CI | Protein ID Gene ID |
Pos | Alignment | Ortho ID | Description |
---|---|---|---|---|---|---|---|
1 | 1 | CI |
YDR051C YDR051C |
315 302 218 206 - - - - - |
mvmeldesinRYVLRtvlpkwtdce ivmeldekddRYVLRttlpkwc--- lvmkkddetqkyhlktrlltwddve iimkrpehthkfellnkmetwhele ......................... ......................... ......................... ......................... ......................... |
Sc_YDR051C Kl_KLLA0F18810g Ca_CAL0004865 Yl_YALI0F11781g Af Nc Sp Cn Ro |
Protein of unknown function; interacts with Hsp82p in two-hybrid assay; deletion confers sensitivity to Nickel |
2 | 1 | CI |
YML127W RSC9 |
466 451 496 495 471 - 599 - 458 |
gk-------kRFVIKgiqprfkalg sk-------kKFVIRgiqprrkals pgeenqapkkKFIIKgiqprqfpvs gt-------kKFIIKgiqprkepvd at--------KFIIKgirpletayt ......................... pv--------eyvingikrrkfpts ......................... en----------------------- |
Sc_YML127W Kl_KLLA0D10461g Ca_CAL0001606 Yl_YALI0F29997g Af_AFUA_6G07810.t1 Nc Sp_SPBC1703.02 Cn Ro_RO3T_09289 |
Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway |
3 | 1 | CI |
YBR118W TEF2 |
421 421 421 422 456 422 421 421 421 |
eafseypplgRFAVRdmrqtvavgv eafsdypplgRFAVRdmrqtvavgv eaftdypplgRFAVRdmrqtvavgv eafteypplgRFAVRdmrqtvavgv esftdypplgRFAVRdmrqtvavgv eaftdypplgRFAVRdmrqtvavgv eaftdyaplgRFAVRdmrqtvavgv etyadypplgRFAVRdmrqtvavgv eaytdypplgRFAVRdmrqtvavgv |
Sc_YBR118W Kl_KLLA0B08998g Ca_CAL0004558 Yl_YALI0C09141g Af_AFUA_1G06390.t1 Nc_NCUT_01155 Sp_SPBC839.15c Cn_cn13119 Ro_RO3T_10089 |
Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes |
4 | 1 | CI |
YPR166C MRP2 |
42 42 42 38 40 40 32 28 26 |
keneilvkslKFIARnmnlptklrl adnevtvkalKFIARnttlpprsrm aehevtrnalKYIARneelpararv aqqeinrralksisqnttlpmkqri eqyeperqalRYIIRnttlpqrvra leaeperqalRYVIRnttlpartra aeheverqsnlyiyrnpelplrvrl eqmevqrraflyvarnttlpatvrh adneivrqafkyitrnetmparvrh |
Sc_YPR166C Kl_KLLA0B10648g Ca_CAL0004723 Yl_YALI0D21626g Af_AFUA_2G02270.t1 Nc_NCUT_00569 Sp_SPAC23H3.07c Cn_cn02283 Ro_RO3T_05687 |
Mitochondrial ribosomal protein of the small subunit |
5 | 1 | CI |
YOR112W CEX1 |
426 419 449 451 433 406 422 468 359 |
terqlnnellRFLAKtqvdsdveir terqlnndllrvlaktqvdkdigir svkqvnqellrilaksqmdpkpsir nsriknndllRYLAKthndkepgir sdrtingellKFLARtandeqpgir sdrtingdllRYLAKtandeqpgir skktlnnellrslavvqndqhptlr sdrilnndllrvlakmqmdtepsir neriinydllKYLAKlqmdpepgir |
Sc_YOR112W Kl_KLLA0F23694g Ca_CAL0001199 Yl_YALI0E27698g Af_AFUA_1G09620.t1 Nc_NCUT_03812 Sp_SPAC15A10.13 Cn_cn08320 Ro_RO3T_01512 |
Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p |
6 | 1 | C |
YHR099W TRA1 |
1939 1953 1929 1961 1891 1880 1884 1802 1761 |
allrsshveaRYLVKqsldvltpvl ailrvhqiearfmvkesldllapvv allrthqtdsRYLVKqaldilapvm allktsqnearqlvkqaldllapvl allrahqnegkalvtqaldvlapvl sllktnqnegrtlvtqalelmapvm silktyqpevrafiefslasllsvl gvlrlkdtdnrvlyrqaidtlassl allrahssearvlvkqgldiiapvl |
Sc_YHR099W Kl_KLLA0F22066g Ca_CAL0003086 Yl_YALI0C02057g Af_AFUA_5G02570.t1 Nc_NCUT_04286 Sp_SPBP16F5.03c Cn_cn01601 Ro_RO3T_02880 |
Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation |
6 | 2 | C |
YHR099W TRA1 |
2624 2616 2649 2668 2647 2638 2548 2465 2528 |
s-lelpphlvkylaisynawyqsin s-lelpphlvrylgitfnawyqsid d-lqlppfaveclasnfdawsqgih g-llmpphllkylgksfdgwfeavk prfkvpphvmkylsrtydawytaas pecrlpphvlkfeaktfdawytalc aklelpphlvkylgklygvyhesvs vpitlpptlvRFLAKnfnawyvgfe pvvqlpahlvkylgkthncwhiaie |
Sc_YHR099W Kl_KLLA0F22066g Ca_CAL0003086 Yl_YALI0C02057g Af_AFUA_5G02570.t1 Nc_NCUT_04286 Sp_SPBP16F5.03c Cn_cn01601 Ro_RO3T_02880 |
Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation |
7 | 1 | C |
YPR119W CLB2 |
346 392 323 380 347 358 321 353 346 |
ctedeikegeKFILKtlkfnlnypn cdeeeikegeKFILKtlefnlnypn ytpeevvqaekymltilnfdlnypn ypedeilraerfilqvlqfnlsypn ftdkeildaerhilatleynmsypn fteaeilsaerfilstlnydlsypn ydeeeilqaeRYILRvlefnlaypn ytveellkaerymlstlqfdmsypn idedelvraecfilqvldfrlcyan |
Sc_YPR119W Kl_KLLA0D15543g Ca_CAL0004596 Yl_YALI0B15180g Af_AFUA_4G12160.t1 Nc_NCUT_01937 Sp_SPBC582.03 Cn_cn10336 Ro_RO3T_03479 |
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
8 | 1 | C |
YHL029C YHL029C |
188 148 248 288 - - - - - |
iietlknaivKFLLKwskifkyesg ----lkecvwqflrkwnkickyesg ---ilenaimkftlkwgkiikydss rfdiyedaiesfltky--hvkyesg ......................... ......................... ......................... ......................... ......................... |
Sc_YHL029C Kl_KLLA0D03861g Ca_CAL0004930 Yl_YALI0C00473g Af Nc Sp Cn Ro |
Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts |
9 | 1 | C |
YGL131C SNT2 |
249 266 298 192 353 449 213 0 128 |
nifyfdelfdrytlkyykvystdki ncfyfnqlfdrytlkyyqmektdqm nqfyfdklfdrymikfydvlstanl nhfyftqfydRYILRfyeivpthtm dsfwydkmfdryihryyevvptkkv dcfwfeklydryiqknyeviptkqi ksyyfdrlfdqninkvfdvvpvtqv ------------------------- dhfyynqlydryiqrvydvvpcetv |
Sc_YGL131C Kl_KLLA0B02178g Ca_CAL0002960 Yl_YALI0E30547g Af_AFUA_1G05240.t1 Nc_NCUT_07306 Sp_SPAC3H1.12c Cn_cn04066 Ro_RO3T_01596 |
DNA binding protein with similarity to the S. pombe Snt2 protein |
10 | 1 | C |
YHR137W ARO9 |
385 402 397 403 - - - - - |
mkeamfegwirwimqiaskynhrkn fngdkvrawlswvmkvageythrrn -----vdgwlewilkmrlnysyrkd --------wlrwclllrnqylerrn ......................... ......................... ......................... ......................... ......................... |
Sc_YHR137W Kl_KLLA0D11110g Ca_CAL0002883 Yl_YALI0C05258g Af Nc Sp Cn Ro |
Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism |
11 | 1 | CI |
YPL137C GIP3 |
947 908 1020 - 884 - - - - |
stkvkkdttkRYLLKkyiekfhilh saklqedstkRYLLKrywekihtih kgkkedikmqriisdsvlertrsir ......................... gddicededepapdedyviggtgvv ......................... ......................... ......................... ......................... |
Sc_YPL137C Kl_KLLA0D07216g Ca_CAL0003186 Yl Af_AFUA_1G12900.t1 Nc Sp Cn Ro |
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments |
12 | 1 | CI |
YOR259C RPT4 |
116 113 107 89 72 69 67 84 75 |
gevmkelseeKYIVKassgpryivg gevmkelseeKYIVKassgpryivg gevlkqlddeRYIVKtssgpryivg gevlkqldeeRFIVKasngpryivg gevlkqldeeRFIVKassgpryvvg gevlkqlddeRFIVKassgpryvvg gevlkqldseRFIVKassgpryvvg gevlkqlddeRFIVKassgpryvvs gevlkqlddeRFIVKntsgpryvvg |
Sc_YOR259C Kl_KLLA0C09592g Ca_CAL0005827 Yl_YALI0E21868g Af_AFUA_6G06780.t1 Nc_NCUT_07349 Sp_SPCC1682.16 Cn_cn10016 Ro_RO3T_05069 |
One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle |
13 | 1 | C |
YER077C YER077C |
631 663 900 - - - - - - |
kgte----rkKFLARrhllrlkqil aedsnsllkrkflfrrhlirlrkri tntsvvvstypklmeqeifryifvk ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YER077C Kl_KLLA0C07689g Ca_CAL0000929 Yl Af Nc Sp Cn Ro |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion |
14 | 1 | C |
YDR457W TOM1 |
383 387 407 381 484 513 367 396 78 |
ishgllfqilRYIAKtlrea----- mshgllfqilkyisklitenn---- vshgilfqclrhiwkmvkdqk---- vshgllmhiirtlisdlkerr---- vnhgvlmfltrkavnelasde--rd vnhgillyviriavaemkedapvdd vsyglmmnlvrdfsknlenpn---- vnhgvlvtffrhlndrlvagea--- anhgiimqilrkvntneeysqs--- |
Sc_YDR457W Kl_KLLA0B01804g Ca_CAL0001517 Yl_YALI0B05940g Af_AFUA_4G10780.t1 Nc_NCUT_08465 Sp_SPAC19D5.04 Cn_cn08122 Ro_RO3T_06596 |
E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators |
14 | 2 | C |
YDR457W TOM1 |
517 521 542 511 628 658 504 528 200 |
relayirsllklvlkllstd----- rqiafirsllklvlkllscd----- rqanyirnlmklvadliqsd----- yragwlktilkfvlqvmptg----- fqqqtlrwmfrfvnhimqhn----g yhqqtlkwllKFIHHvmantysfdg dryfllknllkfvlhliqsg----- cannplktilrsiqrlmqas----- drlsaikamlRFLLRmmess----- |
Sc_YDR457W Kl_KLLA0B01804g Ca_CAL0001517 Yl_YALI0B05940g Af_AFUA_4G10780.t1 Nc_NCUT_08465 Sp_SPAC19D5.04 Cn_cn08122 Ro_RO3T_06596 |
E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators |
15 | 1 | C |
YCR033W SNT1 |
484 525 473 867 - - 79 720 452 |
qkrnkiiseqKYLLKkairnfseyp kpreervknqkylltkpieylfdyp khhesganylkyslarpivdfnefp lprservaemrylrsiplkstrdyk ......................... ......................... lqekylqniyaltqnqlfknvedys geeqdelgaekarelnliasvkaaq eenmddwseeekwskplynsieeyt |
Sc_YCR033W Kl_KLLA0C03564g Ca_CAL0003554 Yl_YALI0B20262g Af Nc Sp_SPAC22E12.19 Cn_cn01044 Ro_RO3T_09691 |
Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein |
16 | 1 | C |
YOL049W GSH2 |
166 165 157 166 174 170 166 167 89 |
glsekvdrlhsylnra-nkydpkg- glstkvgelhdylnks-gnysdng- glsskigqlhqylngt-gqydskyn gltskvadlhrylaat-gaygdda- glsslvrklhselltsppgypisyp glstqtsllhkhlaqh--eypllss gvskavsnlhaycsqs-glyrkpl- alsqragelhKYLAKasrnyydis- slsvrtselhrfllstlkgyggnq- |
Sc_YOL049W Kl_KLLA0F07557g Ca_CAL0002106 Yl_YALI0C17831g Af_AFUA_5G06610.t1 Nc_NCUT_06031 Sp_SPAC3F10.04 Cn_cn10268 Ro_RO3T_00729 |
Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock |
16 | 2 | C |
YOL049W GSH2 |
378 374 371 376 400 400 383 393 252 |
rlal--sepsKYVLKpqregggnnv klal--tepenyvlkpqregggnni klaf--eepeKFVLKpqregggnnv qlar--tepeRFVLKpqregggnni elalnpetavnhvlkpqregggnnv slatsptqcqkyvmkpqregggnnf klaf--ekpedfvlkpqregggnnt klar--qepeRFVLKpqregggnni emal--ekpdelvmkpqreggghni |
Sc_YOL049W Kl_KLLA0F07557g Ca_CAL0002106 Yl_YALI0C17831g Af_AFUA_5G06610.t1 Nc_NCUT_06031 Sp_SPAC3F10.04 Cn_cn10268 Ro_RO3T_00729 |
Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock |
17 | 1 | CI |
YJL107C YJL107C |
345 - - 758 - - - - - |
vhiadilqrhRFILRmcralmmyga ......................... ......................... vhiaellqrqRFILRmcralmlyga ......................... ......................... ......................... ......................... ......................... |
Sc_YJL107C Kl Ca Yl_YALI0E24651g Af Nc Sp Cn Ro |
Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi |
18 | 1 | C |
YNR019W ARE2 |
546 499 513 447 482 478 441 511 - |
fsriwnipvhKFLLRhvyhssmssf fsrlwnrpvhsfllrhvyhssisay fanqwnrcvhKFLLRhvyhssisaf fsrewnipvyqflkrhvyhssisaf fsrewnipvhhflrrhvyfpslsyf fardwnrpvhnfllrhvyhssisam fsrewnkpvhvflmrhvyhssisgf farkwnkpvhtfllrhvyastmttl ......................... |
Sc_YNR019W Kl_KLLA0C09152g Ca_CAL0006272 Yl_YALI0F06578g Af_AFUA_1G06040.t1 Nc_NCUT_03654 Sp_SPAC13G7.05 Cn_cn06362 Ro |
Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen |
19 | 1 | CI |
YGL163C RAD54 |
549 544 496 454 454 461 504 473 446 |
qlqklstivsKFIIRrtndilakyl rlrqlsnivsKFIIRrtnnilakyl klnelsqmvsKFIIRrtndilskyl kllemasivspliirrtndilskyl rlaelsgivnKFIIRrtndilskyl clvellaivnKFIIRrtndilskyl klaelakivnRFIIRrtndilskyl klkelgglvsKFIIRrtndllskyl kvaefwkivsrftirrtndilskyl |
Sc_YGL163C Kl_KLLA0A03069g Ca_CAL0001568 Yl_YALI0B07513g Af_AFUA_6G12910.t1 Nc_NCUT_03186 Sp_SPAC15A10.03c Cn_cn04353 Ro_RO3T_02508 |
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family |
20 | 1 | CI |
YGL084C GUP1 |
416 443 437 423 466 462 437 432 254 |
fwrawhrsynKWVVRyiyiplggsk fwrawhrsynKWVIRyiyiplggsg fwrawhrsynRWVIRyiyipmggsg fwrawhrsfnRWIIRyvygpiggss fwrgwhrsfnRWIVRylyiplggga fwrswhrsfyrwtlryiyiplgg-- fwrawhrsfnRWLIRyiyvplggsn fwrswhrsfnlwvvryiyvpvggsk ----------------------gtk |
Sc_YGL084C Kl_KLLA0E19185g Ca_CAL0000013 Yl_YALI0E30283g Af_AFUA_2G05040.t1 Nc_NCUT_02107 Sp_SPAC24H6.01c Cn_cn06354 Ro_RO3T_14327 |
Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; proposed to be involved in glycerol transport |
21 | 1 | C |
YOR255W OSW1 |
111 107 - - - - - - - |
nlsrlklskrKYALRfyhneifgnn ghlrswisgrkfsmkrivnnas--- ......................... ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YOR255W Kl_KLLA0C09779g Ca Yl Af Nc Sp Cn Ro |
Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p |
22 | 1 | C |
YOR176W HEM15 |
81 77 71 70 99 92 74 90 80 |
isakyqktiaKYIAKfrtpkiekqy isakyqpiiaKYIARfrtpkiekqy fg-rfqnilaKFIAKrrtpkieehy lg-pfqgplakfiawrrtpviekhy lg-rlqsylgpliakrrtpkiqrqy lg-rlqnylgpliskrrtpkiqkqy lgy-fqnslgKFIAKrrtpkvqnhy lp--fqpllapliakrrtpsieeqy fp--mqsmaakfiatrrtpqikeqy |
Sc_YOR176W Kl_KLLA0F20141g Ca_CAL0001790 Yl_YALI0F19470g Af_AFUA_5G07750.t1 Nc_NCUT_08421 Sp_SPCC320.09 Cn_cn06304 Ro_RO3T_05836 |
Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway |
23 | 1 | C |
YAL026C DRS2 |
668 672 676 655 718 720 626 697 542 |
lvqggadlgyKFIIRkgnsvtvll- lvqgaadlgfrfdirrpnsvsist- lvqgaadlgykftirrpkgvtien- lvdgaatlgyafamrkpktigvdvk lvegaaalgyrftnrrprsvlfttn lvdgavqmgyRFVARkpraviiean lvkgaasigyKFLARkphlvtvsif lvagaemlgyrfqtrkpksvfidvn lvkgasmlnykfhtrkpnsiactqr |
Sc_YAL026C Kl_KLLA0A04015g Ca_CAL0004962 Yl_YALI0E34551g Af_AFUA_2G08850.t1 Nc_NCUT_00357 Sp_SPBC887.12 Cn_cn01358 Ro_RO3T_04221 |
Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease |
24 | 1 | C |
YJL109C UTP10 |
1534 1539 1583 1419 1551 1555 1420 1783 1869 |
ieasvheisnsyvlkmndkvfrplf ieasvhqianvyvlklndkvfrplf lessfhgcaiafvmklndksfrplf vqnlfikcliaivlklndktfrplf tedalndvtikmiyklndttfrpif iellinetslkmiyklndaafrpmf vetqavnvflkfvmklsdttfrplf veesaigsflelvtklneptfkplf vegsvitafldlvmklnetlfkplf |
Sc_YJL109C Kl_KLLA0F21208g Ca_CAL0003770 Yl_YALI0E29506g Af_AFUA_6G13370.t1 Nc_NCUT_00342 Sp_SPBC23E6.04c Cn_cn08172 Ro_RO3T_09841 |
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA |
24 | 2 | C |
YJL109C UTP10 |
1664 1669 1712 1537 1685 1686 1545 1919 2008 |
-------sigKYLVKaigalasnns -------vigKYLVKaigslatnns -------sigKYLVKsvstfvtdvs ----vapenskllikavvalcelas s---taatviaeavpaitelavaad -----adnctndlvlavvelaaaad -------lddkvlvkaivelasvas p----spqsprpissclanlagstt tsadylarmntyivpcigqmavtvs |
Sc_YJL109C Kl_KLLA0F21208g Ca_CAL0003770 Yl_YALI0E29506g Af_AFUA_6G13370.t1 Nc_NCUT_00342 Sp_SPBC23E6.04c Cn_cn08172 Ro_RO3T_09841 |
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA |
25 | 1 | C |
YBR203W COS111 |
534 381 387 408 - - - - - |
pfsthhpyanKFLLKyapykdlplg --rshlpftnkfflkyahlrdlplg ----shplinkfllhystskdlpig -fstahpisspflrqystskdvpvg ......................... ......................... ......................... ......................... ......................... |
Sc_YBR203W Kl_KLLA0E23079g Ca_CAL0005497 Yl_YALI0B01166g Af Nc Sp Cn Ro |
Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
26 | 1 | C |
YBR073W RDH54 |
534 540 431 555 518 - - 546 - |
rskemieitkRFILRrtnailekyl rsdqlieitkRFILRrtneilqqyl isqqlieltqsfilrrtqailanyl qsarlssitgqfilrrtadilsrfl rneelreltskfmlrrtvdilakyl ......................... ......................... randlaklskefvlrrtaavlenyl ......................... |
Sc_YBR073W Kl_KLLA0F11814g Ca_CAL0004359 Yl_YALI0E24431g Af_AFUA_1G15120.t1 Nc Sp Cn_cn03333 Ro |
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference |
27 | 1 | CI |
YDR489W SLD5 |
137 133 102 130 100 89 83 - - |
lcmetelerlKFVIRsyircrlski lcmeaelerlKFLVRsfircrlski miietdlerlnyivrlyirtrlskl liveteleriKYLIRsylrvrllki silqtdlsrtqflirsflrqrlakl iviqtelerfKYLVRsflrtriaki vlmqtelervKFVLRsymrtrinki ......................... ......................... |
Sc_YDR489W Kl_KLLA0F11121g Ca_CAL0000861 Yl_YALI0B17820g Af_AFUA_6G08210.t1 Nc_NCUT_09082 Sp_SPBP4H10.21c Cn Ro |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery |
28 | 1 | C |
YOL008W COQ10 |
45 46 26 34 79 - 14 86 - |
----htireqRYVLRkainappstv ----sskdeqhyvlkrnirgtpnev -------kpqsyeiskilhgspkqv --------pttfsvtqrfnyppgli ----dnnksrvltatrtlpyqpsal ......................... -------------asrlmpykpsfl qgvevdgevqryharkilpysqaql ......................... |
Sc_YOL008W Kl_KLLA0C06050g Ca_CAL0004083 Yl_YALI0A02563g Af_AFUA_6G07220.t1 Nc Sp_SPCC16A11.07 Cn_cn05160 Ro |
Coenzyme Q (ubiquinone) binding protein, functions in the delivery of Q<sub>6</sub> to its proper location for electron transport during respiration; START domain protein with homologs in bacteria and eukaryotes |
29 | 1 | C |
YDR125C ECM18 |
244 206 259 - - - - - - |
ghsfggylsfKYAVKypnsvnklcl ghsyggyltfkyslkypdnvhklcl ghsfggywcgsyalkypenvnnlvl ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YDR125C Kl_KLLA0F19624g Ca_CAL0000311 Yl Af Nc Sp Cn Ro |
Protein of unknown function, similar to Rlp24p |
30 | 1 | C |
YFL049W SWP82 |
40 26 - 0 - - - - - |
vpkilirehervilkqilqildqde vpeyviknhelfilkttlsilnnpe ......................... ------------------------- ......................... ......................... ......................... ......................... ......................... |
Sc_YFL049W Kl_KLLA0D05885g Ca Yl_YALI0E06369g Af Nc Sp Cn Ro |
Member of the SWI/SNF chromatin remodeling complex in which it plays an as yet unidentified role; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p |
31 | 1 | C |
YPR018W RLF2 |
583 562 559 500 628 669 531 797 - |
rssgkgdlprKWVIKdaqnwenlra kst-kgd--rrwevkdmnnwehlks ydk-kss---kweikaemkekycs- rqgpksd--kRWVLKdi-------- rvg-qrevdkkwvcn---------- vfaskhpdmvraqikasfesmtekq rkgksvs--dgwiikenfasllss- regrskdsvwrvyreawiaaglepa ......................... |
Sc_YPR018W Kl_KLLA0D02090g Ca_CAL0004223 Yl_YALI0F21637g Af_AFUA_5G03720.t1 Nc_NCUT_03891 Sp_SPBC29A10.03c Cn_cn03648 Ro |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin |
32 | 1 | C |
YPR031W NTO1 |
605 580 601 637 827 824 529 - 602 |
kvfdivkspqKYLLKinvldifiks iindiafhpiRYILKdvvwnnltkt dvvdsvyfplkqlieltimrlnnkf elirtlllpvtalclrlcdemteqd sivdtvyfpifpllwpiyekaqgld dfvdscyfpvyemlipalqkaiqsd kflnlnyfpaqrllqdtlvkiidld ......................... ayldlilfpldyiigpvldqise-- |
Sc_YPR031W Kl_KLLA0E06491g Ca_CAL0003263 Yl_YALI0D25674g Af_AFUA_7G05250.t1 Nc_NCUT_00042 Sp_SPBC17D11.04c Cn Ro_RO3T_03265 |
Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 |
33 | 1 | C |
YLL040C VPS13 |
2321 2291 2266 2392 2359 2401 2262 2348 2300 |
llskvieiapryiisntldipievc rftkiveispryifrnstsevieim nltkvisitpryifvnkleeelqiv kltrfieltprfiihnclkeelrir kmtkvvtispRFILKnklseeilvr kmvktvtlapryviqnrlgedinir sktnivtitsRFIVRnktrwslvia kltkvitiapRFLVKniysrpikir klnklitltprfvlsnqmdqniryr |
Sc_YLL040C Kl_KLLA0E00705g Ca_CAL0001755 Yl_YALI0F06791g Af_AFUA_4G11560.t1 Nc_NCUT_05723 Sp_SPBC21C3.01c Cn_cn03502 Ro_RO3T_13642 |
Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention |
34 | 1 | C |
YLR045C STU2 |
479 460 448 426 427 405 425 438 - |
ktpqirmectqlfnasmk---eekd kvpqvkivcskflfellsnwtptet ktpqnkiasanfvkrcls------t ktpqvrieslnfilrlls------t knpqvkqetlKFLIRclr------t knpqvkegtmKFLVRclr------t knpqiksscfslfsrsfs------n knpqvkegtlkflhrslq------t ......................... |
Sc_YLR045C Kl_KLLA0E16325g Ca_CAL0003948 Yl_YALI0E28371g Af_AFUA_6G12980.t1 Nc_NCUT_05461 Sp_SPCC895.07 Cn_cn07265 Ro |
Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p |
35 | 1 | C |
YOR126C IAH1 |
57 59 63 53 65 53 82 51 35 |
lqrgfkgytsRWALKilpeilkhes vqrgfsgynsRWALKllpkileqeq inrgfsgynseharqilpkileset lvrgysgyntdqavqffhhilehek inrgfggystahavkvfpkffpkpe vnrglsgyntsnalkllpqifsppg dvwgfsgytsrhvlrylpeipleid inrgfggynsewaipvfeqvfatkk vnrgfsgfntdwampilkqllptte |
Sc_YOR126C Kl_KLLA0E02509g Ca_CAL0000954 Yl_YALI0B07227g Af_AFUA_2G08920.t1 Nc_NCUT_00404 Sp_SPCC126.10 Cn_cn12157 Ro_RO3T_08748 |
Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing |
36 | 1 | CI |
YNL080C EOS1 |
160 147 - 114 - - 85 - - |
syaildslmvRWIVKystvaailrm sysildslmvRWIIKyatmaaifrm ......................... ayavldglmirwivtystpaaivrm ......................... ......................... sfvlangfllkwlihysigptiirl ......................... ......................... |
Sc_YNL080C Kl_KLLA0E17909g Ca Yl_YALI0D01936g Af Nc Sp_SPAPB17E12.08 Cn Ro |
Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene |
37 | 1 | CI |
YBR235W YBR235W |
525 513 - 533 580 466 539 - - |
sqsliyhqvrKYLLRlr--qdniky sqsliyhqvrKYLLRlr--qdnvky ......................... sqallyhqvrKYLLRlr--qdhvkf sqsliyhqvrKYLLRlr--qehvkf sqnliyhqvrKYLLRlk--pehikf sqgiiyhqlrkyllqtnkarenikf ......................... ......................... |
Sc_YBR235W Kl_KLLA0F10549g Ca Yl_YALI0B04378g Af_AFUA_4G07770.t1 Nc_NCUT_03469 Sp_SPBC18H10.16 Cn Ro |
Putative ion transporter, similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family; YBR235W is not an essential gene |
38 | 1 | CI |
YGL099W LSG1 |
485 494 504 554 505 485 449 548 465 |
ygsadeprasRYILKdyvngkllyv fgaadesrasRYILKdyvngkllyi fgsadepraaRYILKdyvngkllyv qgnpdesraaRYVLKdyvngkllyc qgqpdesraaRYVLKdyvngkllfc lgqpdqsravRYILKdyvngkllyc hgtpddsraarillkdyvngkllyv fgmpdtsraaRYVLKdyvnakllfa qgnpdearaaRYILKdyvngkllfc |
Sc_YGL099W Kl_KLLA0F06666g Ca_CAL0005034 Yl_YALI0C21956g Af_AFUA_5G06510.t1 Nc_NCUT_03922 Sp_SPAC3F10.16c Cn_cn03586 Ro_RO3T_09763 |
Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm |
39 | 1 | CI |
YKL112W ABF1 |
428 254 - - - - - - - |
iarrittykaRFVLKkkkmgeyndl iarrvttykaRFVLKrkkdgvy--- ......................... ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YKL112W Kl_KLLA0F02970g Ca Yl Af Nc Sp Cn Ro |
DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair |
40 | 1 | CI |
YDL191W RPL35A |
115 115 115 118 181 119 117 122 115 |
rkkqiafpqrKYAIKa--------- rkkqiafpqrKYAIKa--------- rkqriafpqrKFAIKa--------- tkkqthfpqrRYALKa--------- rkkeihfpqrKYAVKtnvvsgseme kkrtthfplrKFAVKaa-------- ikkeryfplrKYALKa--------- hkknihfpkrkialka--------- qkkeahfplrKYAVKa--------- |
Sc_YDL191W Kl_KLLA0F05247g Ca_CAF0007060 Yl_YALI0A09922g Af_AFUA_1G10510.t1 Nc_NCUT_01988 Sp_SPCC613.05c Cn_cn01742 Ro_RO3T_11228 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein |
41 | 1 | CI |
YKL103C LAP4 |
261 268 259 235 262 269 - - - |
lfgkhcihllRYVAKlagve-vsel lygkhsihllRYIAKllsvk-vsai lygkhplkllRYIAKlanvs-vgdi lvgkhsidllrtlskhsgva-vkdm faatqperlvkiiskelgitdydti fvstqppklvkliasqlkledytni ......................... ......................... ......................... |
Sc_YKL103C Kl_KLLA0F13574g Ca_CAL0006379 Yl_YALI0C10494g Af_AFUA_5G03990.t1 Nc_NCUT_03897 Sp Cn Ro |
Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway |
42 | 1 | C |
YKL176C LST4 |
199 146 242 - - - - - - |
----------qyn-riaislcipri ----------kstlriaisccvtdd dtsknnnvnsrfaigivipleslgs ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YKL176C Kl_KLLA0A06622g Ca_CAL0002848 Yl Af Nc Sp Cn Ro |
Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface |
42 | 2 | C |
YKL176C LST4 |
237 185 281 - - - - - - |
wltqtqkmligfltknrimqentgn fldqcentllKYLAKn--------- ytinlqkliykkllvhlnqgltyds ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YKL176C Kl_KLLA0A06622g Ca_CAL0002848 Yl Af Nc Sp Cn Ro |
Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface |
43 | 1 | C |
YDL169C UGX2 |
219 180 - - - - - - - |
dsdtpennhlKWLIK---------- esetlenkllkslvrs--------- ......................... ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YDL169C Kl_KLLA0E19493g Ca Yl Af Nc Sp Cn Ro |
Protein of unknown function, transcript accumulates in response to any combination of stress conditions |
44 | 1 | C |
YJL090C DPB11 |
57 57 57 53 78 - 58 - - |
vgsttntnkfKFAVKhrfdiifidi vg-elftakynfavknrtdivfvsp vg-drdtekyrfcikyrpdiifida vg-nqdsekylfashqrldmtflhp vg-eintakyKFVARersdvvvlkp ......................... ag-dfdtpkykfaaksrpdikimss ......................... ......................... |
Sc_YJL090C Kl_KLLA0F14300g Ca_CAL0004555 Yl_YALI0E21978g Af_AFUA_5G13380.t1 Nc Sp_SPAC23C4.18c Cn Ro |
Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis, also required for S/M checkpoint control |
45 | 1 | C |
YPR105C COG4 |
390 347 402 324 457 482 353 452 155 |
qilqnwsmysrfysvkwnefsdlhp nflqnwsmycqffsmkwlqftngsv sifenwtlycrfitvkylqepkhrq milnrwalyrkflagfegg------ vmlsrwslycrfiaetcnvryltas imlsrwsayshllaqkc-------- aivskwniskifisrlvlrlsqsdg alggrwalfrrfiwsriadededes elmnsylvideyllkks-------- |
Sc_YPR105C Kl_KLLA0F08184g Ca_CAL0005896 Yl_YALI0D03113g Af_AFUA_2G05890.t1 Nc_NCUT_02785 Sp_SPCC338.13 Cn_cn13146 Ro_RO3T_08984 |
Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments |
46 | 1 | CI |
YGL137W SEC27 |
62 62 62 62 62 62 63 64 64 |
qvtetpvragKFIARknwiivgsdd plcdapvragRFIARknwvvvgsdd qvtelpvragKFIARknwivvgsdd evadvplragRFIARknwiivgsdd eltdvpvragRFIARknwivcgsdd eltdvpvragRFIARknwiicgsdd dindvpiracafiarknwfvcgsdd evtdvpvrcvRYIARknwfvsgsdd evsetpvraakfvprknwiitgadd |
Sc_YGL137W Kl_KLLA0B01958g Ca_CAL0005039 Yl_YALI0C21802g Af_AFUA_2G10610.t1 Nc_NCUT_07117 Sp_SPBC16C6.13c Cn_cn02021 Ro_RO3T_06159 |
Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP |
47 | 1 | CI |
YLR180W SAM1 |
286 - - - - 298 - 301 286 |
kvdrsaayaaRWVAKslvaaglckr ......................... ......................... ......................... ......................... kvdrsaayvgRWIAKslvaaglarr ......................... kvdrsaaytaRWIAKslvaaglarr kvdrsaaytaRWIAKslvnaklcrr |
Sc_YLR180W Kl Ca Yl Af Nc_NCUT_02041 Sp Cn_cn01393 Ro_RO3T_03742 |
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p) |
48 | 1 | C |
YBR038W CHS2 |
576 531 633 596 650 952 - 652 462 |
cwelvakrdaKWVLKyvkeatgetd cwelvakrdeawvlkyvkeatgetd cwelvskrndnwvlkfvksatgetd cwelvaklnekwmlkyvpsatgetd cwelvakreeRWVLKfvksavgetd cwelvakrgeRWVLKyvkgctgetd ......................... cwelvskrqckwklhyvksayaitd cyelvakkeanwvlhyvsssygetd |
Sc_YBR038W Kl_KLLA0D03542g Ca_CAL0002701 Yl_YALI0B16324g Af_AFUA_4G04180.t1 Nc_NCUT_05007 Sp Cn_cn03728 Ro_RO3T_16229 |
Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis |
49 | 1 | CI |
YPR080W TEF1 |
421 - 421 - - - 421 - 421 |
eafseypplgRFAVRdmrqtvavgv ......................... eaftdypplgRFAVRdmrqtvavgv ......................... ......................... ......................... eaftdyaplgRFAVRdmrqtvavgv ......................... eaytdypplgRFAVRdmrqtvavgv |
Sc_YPR080W Kl Ca_CAL0004916 Yl Af Nc Sp_SPAC23A1.10 Cn Ro_RO3T_15046 |
Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes |
50 | 1 | CI |
YGR240C PFK1 |
876 854 897 - 691 - - - - |
psskdrvtasRFAVKcikfieqwnk psskdrviasRFAVKcvkfieqwnk psandrvmavkfslkamefietrng ......................... pspmdriralrmavkcmlhlenyag ......................... ......................... ......................... ......................... |
Sc_YGR240C Kl_KLLA0A05544g Ca_CAL0003055 Yl Af_AFUA_4G00960.t1 Nc Sp Cn Ro |
Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes |
51 | 1 | CI |
YDR208W MSS4 |
492 413 436 839 481 381 375 497 253 |
gsffyysrdyKYIIKtihhsehihl gsffyfsrdyKYIIKtihhsehkhl gsffyysrdfRFIIKtihhsehkql gsffyfsrdyRFIIKtihhsehkql gsffyfsrdyKYIIKtihhsehkll gsffyfsrdyKYIIKtihhaehkfl gsffyfsrdyRFIIKtihhsehkfl gsffyfsrdyRFIIKtiahsehkfl gsffyysrdyRFIIKtihytehkfm |
Sc_YDR208W Kl_KLLA0A04301g Ca_CAL0002340 Yl_YALI0F23573g Af_AFUA_3G06080.t1 Nc_NCUT_03131 Sp_SPAC19G12.14 Cn_cn01363 Ro_RO3T_04373 |
Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation |
52 | 1 | C |
YBR245C ISW1 |
89 27 25 - - 66 - - - |
pphdpesnkkRYLLKd---angk-k pnsiae-kkeryllplrdlasgkrk ----rnklsfqdnaskyftktekqq ......................... ......................... pvdgrrkrseanqlrrsifgkkhdr ......................... ......................... ......................... |
Sc_YBR245C Kl_KLLA0F06710g Ca_CAL0001816 Yl Af Nc_NCUT_03554 Sp Cn Ro |
Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation |
53 | 1 | C |
YMR176W ECM5 |
692 741 813 741 786 757 573 - 540 |
lrfssea--akwtskmgflpgldvn vnnipda--elwraenkllpsilpf lnyales--eKWLAKqniipgfstf ldg-paqecaslyskysqlpafsye epwgamg--verlqafrrhpcfshd epfghag--verlqtfrrqpcfshd ikdgllnssisvlksmripssvsye ......................... vdyglec--vkrykefrrqpcfshd |
Sc_YMR176W Kl_KLLA0C16203g Ca_CAL0001611 Yl_YALI0C16390g Af_AFUA_5G03430.t1 Nc_NCUT_04019 Sp_SPBP19A11.06 Cn Ro_RO3T_13099 |
Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks |
54 | 1 | C |
YPL106C SSE1 |
623 623 626 619 - - 632 626 615 |
-degfdsikaKYIAKyeelaslgni -ddgydstkgKYIAKyeelasignv -edgedstkaKYIAKyeelasignv -gagedakkalyiakyeelasignl ......................... ......................... -eegedttkavytakledlmrvggp sedgedatksayvqkldalkamgdp -degydasksvyveklealkkignp |
Sc_YPL106C Kl_KLLA0E24597g Ca_CAL0001523 Yl_YALI0E13255g Af Nc Sp_SPAC110.04c Cn_cn13198 Ro_RO3T_06487 |
ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm |
54 | 2 | C |
YPL106C SSE1 |
641 641 644 637 - - 650 644 633 |
laslgniirgRYLAKeeekkqairs lasignvirgRYLAKeeekkqalra lasignvikgRYLAKeqekkeqyrq lasignlikgrynakqeeerqakva ......................... ......................... lmrvggpirqryldaeeakrqk--- lkamgdpivlrwkesedrpraaaal lkkignpvveryreaeerphaeral |
Sc_YPL106C Kl_KLLA0E24597g Ca_CAL0001523 Yl_YALI0E13255g Af Nc Sp_SPAC110.04c Cn_cn13198 Ro_RO3T_06487 |
ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm |
55 | 1 | C |
YNL248C RPA49 |
241 238 220 234 290 277 257 256 249 |
lelfpyqnnsKYVAKkldsltqp-- leyfpyt-kfqyvanklptltqa-- leklpft-ksefiakqlpilisq-- vdmlpyr-tsqmvrdslykitdkt- -aglpvattsryvsrrveavvksg- lediqvp--sRFVAKrvsnvassd- akllpyr-hslfinerfqrllsie- asalpykrsswlqyksravanikdk kshlayr-dskfindrlmaiiaasg |
Sc_YNL248C Kl_KLLA0C02959g Ca_CAL0004338 Yl_YALI0E05225g Af_AFUA_5G06280.t1 Nc_NCUT_06254 Sp_SPAC2F3.03c Cn_cn02440 Ro_RO3T_15617 |
RNA polymerase I subunit A49 |
56 | 1 | C |
YBL037W APL3 |
73 58 56 54 50 66 52 51 0 |
hdrlggyqrkKYVAKlayiyitsnt -sglngyqrkKYVAKmayiyittna --nlngyqkkkyvckliyiylignp --nlsgyqkkkyvgkllyiyilg-- --nlngyqkkkyvckllyvyiqg-- --slsgyhkkkyvckllyiyilg-- --tlsaydrkkyvskllyiymlg-- --nldgyqkkKYLAKvvftyilg-- ------------------myilg-- |
Sc_YBL037W Kl_KLLA0B12243g Ca_CAL0004290 Yl_YALI0C18623g Af_AFUA_4G04310.t1 Nc_NCUT_02613 Sp_SPBC691.03c Cn_cn07414 Ro_RO3T_03040 |
Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport |
57 | 1 | CI |
YFR019W FAB1 |
2055 1833 2402 1818 2256 2296 1709 2197 1997 |
gsgflktlddRFIIKelshaeleaf gsaflktlddRFVIKelshseldaf gssflktldnRYILKelskselesf gsaflktlddrlvvkqlspaeldaf nslflktlddRFILKslspietqaf ksvflktlddrlvmkslspvetsaf gsaflktfdkKYILKvlsrlesdsl gsaflksrddRFIAKeitryemdal gsaflktkddrllmkqmskyeldaf |
Sc_YFR019W Kl_KLLA0D04598g Ca_CAL0005404 Yl_YALI0E29161g Af_AFUA_6G07440.t1 Nc_NCUT_01238 Sp_SPBC3E7.01 Cn_cn04307 Ro_RO3T_10566 |
1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis |
58 | 1 | C |
YNL193W YNL193W |
455 377 428 - 399 - 367 - - |
lvnssdnelrRYAIKeste-----k minradnelsrcllkqtelnqlqgq iiaradielqrssinnyss------ ......................... hmargdvemhrwrlglapwey---- ......................... lisradleiqr-------------- ......................... ......................... |
Sc_YNL193W Kl_KLLA0F20944g Ca_CAL0001137 Yl Af_AFUA_5G04150.t1 Nc Sp_SPAC926.02 Cn Ro |
Putative protein of unknown function; exhibits a two-hybrid interaction with Yhr151cp in a large-scale analysis |
59 | 1 | CI |
YHR059W FYV4 |
85 78 104 75 92 - 80 - - |
ekgvn-iqqrKYILKqvhnyr---- ekgip-iqqrryilnqveklr---- nmgid-trarRYLLRwrhkfln--- ekgie-ardrryimtqlyryk---- evgieparqrRYLLRkrekfrqgiy ......................... kegid-vrtrkyiasqrnrfk---- ......................... ......................... |
Sc_YHR059W Kl_KLLA0C10164g Ca_CAL0004161 Yl_YALI0E32747g Af_AFUA_7G03730.t1 Nc Sp_SPBC4B4.11 Cn Ro |
Protein of unknown function, required for survival upon exposure to K1 killer toxin |
60 | 1 | C |
YKL028W TFA1 |
14 14 10 9 9 9 13 20 0 |
piddivknllKFVVRgfyggsfvlv pieetikallsfvirqfypnsyvlv -mddsvrslirfvsrgfystpyvli --mdnikrllqyvtrgfydtksilv --mdlantlirtvvrafyetrqili --mdiaktlircvmrafystqeili napeivqrlikmimrafyetrhiif eiqklcsdlvyqvaysfydvpyiii ------------------------- |
Sc_YKL028W Kl_KLLA0E18657g Ca_CAL0005399 Yl_YALI0F26367g Af_AFUA_2G08450.t1 Nc_NCUT_04339 Sp_SPAC458.07 Cn_cn03337 Ro_RO3T_01562 |
TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening |
61 | 1 | CI |
YLR106C MDN1 |
1276 1275 1287 1177 1268 1300 1094 1290 - |
nsfatlrdlfRWALRdavgyeqlaa nsfatlrdlfRWALRpavgyeelaa nsfatlrdlfrwamrdavgyeelaa -afatlrdlfrwagrncdnneelam nsfatlrdlfRWALRraddreqlav nsfatlrdlfRWALRaaetrqdiad nsfatlrdlfrwafreavgyqqlae qsfatlrdlfrwaergaigyqqlae ......................... |
Sc_YLR106C Kl_KLLA0F19888g Ca_CAL0003858 Yl_YALI0B08338g Af_AFUA_2G12150.t1 Nc_NCUT_06238 Sp_SPCC737.08 Cn_cn10211 Ro |
Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm |
62 | 1 | CI |
YBR108W YBR108W |
27 28 - - - - - - - |
sagkygyqgtKYVAKtgykaskkhy sagkygyqgtKYVAKagykaskthy ......................... ......................... ......................... ......................... ......................... ......................... ......................... |
Sc_YBR108W Kl_KLLA0B09460g Ca Yl Af Nc Sp Cn Ro |
Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media |
63 | 1 | C |
YJL012C VTC4 |
296 297 304 295 308 338 294 342 891 |
dwtgeksvkaRFALKerhvndflkg dwtgeksvkaRFALKekyvndflhg dwtgeksvkaRFALKekkvnqflsg dwtgeksvkarfnlkekhvndfmag dwtgeksvkarfslkekhvnaylsg dwtgeksvkaRFALKeklvnpylrg dwtgeksvkarfplkekyvnaflrg dwtgeksvkerftikegkmndfisg swtgeksvkarfpikekylnaflkg |
Sc_YJL012C Kl_KLLA0F22627g Ca_CAL0004171 Yl_YALI0C10945g Af_AFUA_2G09040.t1 Nc_NCUT_09629 Sp_SPCC1322.14c Cn_cn04250 Ro_RO3T_16785 |
Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion |
64 | 1 | C |
YOL129W VPS68 |
136 128 134 136 126 132 123 141 129 |
lsgsivvliiKFLVKdyntyptlgm isgslvvlivKFLLKdytsyptlgm lagsfmvfilkylmnhy-tfptlgm massiavlvlkyalpgy-smptlgm lagsvtvmvlKYLIKqy-plptlyf maggvtvfvlKYVVKdv-gfpalrm lggsftvfilkyvvagy-egksllm lagslcvlilkyivpdytg--ytyy lagsccvlivkyiihldssqpyiny |
Sc_YOL129W Kl_KLLA0E07415g Ca_CAL0005014 Yl_YALI0D20944g Af_AFUA_6G04760.t1 Nc_NCUT_03901 Sp_SPBC8D2.02c Cn_cn02565 Ro_RO3T_00165 |
Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria |
65 | 1 | CI |
YMR109W MYO5 |
520 518 532 521 553 520 525 526 518 |
tnphfdlrsnKFVIKhyagdvtydi tnahfdlrssKFVIKhyagdvtydi snrhfedrrgKFIIKhyagdvtydv qnphfeqrqrKFVIKhyagdvtydv -npnfenrqgqfiikhyagdvsyav -nphltprqgafivkhyagdvtysv -nphfeqrqnqfivkhyagdvtysi -npnfeargnKFLIKhyagdvlytv -nphfesrgsKFLIRhyagdvlyni |
Sc_YMR109W Kl_KLLA0B12562g Ca_CAL0001808 Yl_YALI0E02046g Af_AFUA_8G05660.t1 Nc_NCUT_01269 Sp_SPBC146.13c Cn_cn09230 Ro_RO3T_15775 |
One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization |
66 | 1 | CI |
YML098W TAF13 |
69 69 83 73 - 75 74 - 78 |
qrnklrledfKFALRkdpiklgrae krnkikvedfRFVLRkdevklgrae nrtrvklndlaftlrndpmklarfr grqkikvddfKFLLRndprklgrae ......................... grqkvkfedfefamrrnprfmgkiq -rnkvkvddfKFALRddpkklgrve ......................... -rgkvkvedfKFVLRkdtkklarve |
Sc_YML098W Kl_KLLA0D10219g Ca_CAL0002660 Yl_YALI0D09625g Af Nc_NCUT_02632 Sp_SPCC1494.02c Cn Ro_RO3T_03275 |
TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors |
67 | 1 | CI |
YDL164C CDC9 |
300 251 314 285 434 433 300 337 243 |
-------ieaKFLIRslesklrigl -------yeaKFLIRslesklrigl -------seaKFLIRslqgklrigs -------neaKFIIRslegklrigl --------eaKFIVRflegklrlgl tkdkggpseaKFIVRflegklrlgl --------epKYLIRalegklrlql --------eaKFIIRslegklrigl --------eaKYIIRqlegklrigl |
Sc_YDL164C Kl_KLLA0D12496g Ca_CAL0006047 Yl_YALI0F01034g Af_AFUA_2G09010.t1 Nc_NCUT_06250 Sp_SPAC20G8.01 Cn_cn08403 Ro_RO3T_07347 |
DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination |
68 | 1 | C |
YLR382C NAM2 |
569 556 521 503 613 613 555 - 492 |
ehailhllysRFIAKflgsinawsd ehailhllysrfiskftasigmwdg ehailhllysRFIAKflsdcglwdg ehailhllyaRFVAKfladkgywsg ehailhllyarfiykflsqtelfpe ehailhllysrfiykflmtssfagk ehsilhllysrffskfmkdiglwng ......................... ehailhllysrfiskvllkqgayqq |
Sc_YLR382C Kl_KLLA0E05325g Ca_CAL0001358 Yl_YALI0F02299g Af_AFUA_6G04910.t1 Nc_NCUT_03498 Sp_SPAC4G8.09 Cn Ro_RO3T_15723 |
Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance |
68 | 2 | C |
YLR382C NAM2 |
695 678 643 624 741 746 677 - 596 |
wdeskivgierwlqkvlhltknils wdeskivgierwlermlkfc---is wqeeqisgtdrwlrrviqlgdsite wdegkivgikRWLLKvksitesvvk wddtkivgierwfgrlwklvldakq wdeskitgvtrwlsrvhdlvqkiac wnenaimgtkrwltkiwncvhqlle ......................... wddtsivgmqRWLAKvlkls----- |
Sc_YLR382C Kl_KLLA0E05325g Ca_CAL0001358 Yl_YALI0F02299g Af_AFUA_6G04910.t1 Nc_NCUT_03498 Sp_SPAC4G8.09 Cn Ro_RO3T_15723 |
Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance |
69 | 1 | I |
YLR256W HAP1 |
622 503 477 416 - - - - - |
tpvealelcqKYLIKfdelssisnn tpietveivrKFLIKfdeissfans inidvvsvaqecfnqfnimr----- awtewlkgidhcleqamvcvr---- ......................... ......................... ......................... ......................... ......................... |
Sc_YLR256W Kl_KLLA0F22990g Ca_CAL0002550 Yl_YALI0C18667g Af Nc Sp Cn Ro |
Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus |
70 | 1 | CI |
YLR089C ALT1 |
124 62 48 40 38 22 - 48 - |
edvnenvlkaKYAVRgaipmraeel ddvnenvlkaKYAVRgripmraeel hdinpqtveaKYAVRgkipiiadel kdlnpqvvnaqyavrgklavradei dninpnvkaaKYAVRgelavkaeey dninphvraaKYAVRgelavkseef ......................... dtinpavqavhyavrgelaikadky ......................... |
Sc_YLR089C Kl_KLLA0F19162g Ca_CAL0004796 Yl_YALI0D06325g Af_AFUA_6G07770.t1 Nc_NCUT_03635 Sp Cn_cn07331 Ro |
Putative alanine transaminase (glutamic pyruvic transaminase); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
71 | 1 | C |
YKR026C GCN3 |
75 75 75 75 86 97 88 98 60 |
slragcdifmRFVLRnlhl------ slragcdifmRFVLKnthl------ slsagcdlfmRFVLRntnv------ slsagcdlfmRFVLRnire------ glsagtdlfqrylittlqrpgqlgp pllagadlfeqyllrslrg----qt slsagcdifqrfvtrslhd------ gvragcqlwerffalfpgv------ ------------------------- |
Sc_YKR026C Kl_KLLA0F13970g Ca_CAL0000120 Yl_YALI0C18161g Af_AFUA_5G11340.t1 Nc_NCUT_05286 Sp_SPCC11E10.07c Cn_cn03560 Ro_RO3T_06935 |
Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression |
72 | 1 | C |
YHL030W ECM29 |
363 352 384 316 361 359 301 - 243 |
klrsltlsfirhvaklnyknlnpas rvklaalvfirhvaknnhlalrett rlrslaiqfirklgqspvpeenlek ysraaiiqfvnwivkhsneelflrh klrtqiftfttwvvrmgsp-sdlkl kvhralfefinwvarigaskpefsk smqprliqftrwvvdkadpnflkpk ......................... slspvapiivsgllkfinqleeaqg |
Sc_YHL030W Kl_KLLA0E00727g Ca_CAL0004949 Yl_YALI0C03828g Af_AFUA_6G06540.t1 Nc_NCUT_00776 Sp_SPAC1782.01 Cn Ro_RO3T_02505 |
Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome |
73 | 1 | CI |
YDR502C SAM2 |
288 288 289 290 291 - 286 - - |
kvdrsaayaaRWVAKslvaaglckr kvdrsaayaaRWVAKslvhagickr kvdrsaayaaRWVAKslvtaglakr kvdrsaayaaRWVAKslvkaglarr kvdrsaayvgRWIAKslvhaglarr ......................... kvdrsaayaaRWIAKslvaaglarr ......................... ......................... |
Sc_YDR502C Kl_KLLA0C01782g Ca_CAL0001034 Yl_YALI0B14509g Af_AFUA_1G10630.t1 Nc Sp_SPBC14F5.05c Cn Ro |
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p) |
74 | 1 | CI |
YGR124W ASN2 |
450 - 450 443 498 460 437 - 445 |
mikpkegrieKYILRkafdttdepd ......................... liqp--gkieKYILRkafdtsdepd iidk--dhiekysirkafdtsdepg mitk--erieKYILRkafdtsdepd mitk--ekleKYILRkafdtkdqpe my--ingrkeKYILRkafdtthdss ......................... lhdrsqgrmeKYILRkafddes--- |
Sc_YGR124W Kl Ca_CAL0003290 Yl_YALI0A13387g Af_AFUA_4G06900.t1 Nc_NCUT_03787 Sp_SPBC119.10 Cn Ro_RO3T_15933 |
Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway |
75 | 1 | C |
YHR116W COX23 |
91 62 74 60 - - - 36 - |
ddpenpvnkyKFALKadsqyydpce ddpestlnryRFAVKgaseyydpcq dnpkshrhkykwsmkepskfydpce ddptamsnrvqflakadsqyydpca ......................... ......................... ......................... eipedykktfr-grgtvskfvdpce ......................... |
Sc_YHR116W Kl_KLLA0F24024g Ca_CAL0003316 Yl_YALI0B10274g Af Nc Sp Cn_cn14137 Ro |
Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p |
76 | 1 | C |
YPL125W KAP120 |
763 762 745 745 775 1398 750 767 - |
tfqdifkqmsKYLLKlredsfqlvl afteilkhaasyllllrddsytill laseifqvignylskmrddayaifi -----htllsifgkymdilsfdvvq rlpllvsfetllqsttrqrigvvpr rrptlaalvktldarsreqsqtgar -----ftifeklndllddvknetlq ---qaiasnlamalststgnesavi ......................... |
Sc_YPL125W Kl_KLLA0D06633g Ca_CAL0003089 Yl_YALI0B00198g Af_AFUA_1G03590.t1 Nc_NCUT_01223 Sp_SPCC1322.06 Cn_cn12143 Ro |
Karyopherin with a role in the assembly or export of 60S ribosomal subunits |
77 | 1 | C |
YOR260W GCD1 |
406 338 306 312 428 418 344 407 295 |
nnlnaymdanRFVLKiksqtmftkn nslsaymesnRYVLKik-qtaiqqr nnlpvlmeanryfmkkqaiaksasq nnlsaymemnrvilkarakanataq dtsalllsvslrlaklesieevg-r dtaqlllqislqlaklpsieevgsa nnlpnyfelnkciak---------- nslagywelnrrfikslssttpaak ntiasyselnryvtk---------q |
Sc_YOR260W Kl_KLLA0C09570g Ca_CAL0005825 Yl_YALI0E21846g Af_AFUA_1G16660.t1 Nc_NCUT_02713 Sp_SPAC4D7.09 Cn_cn08385 Ro_RO3T_10989 |
Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression |
78 | 1 | CI |
YDL136W RPL35B |
115 - - - - - - - 115 |
rkkqiafpqrKYAIKa--------- ......................... ......................... ......................... ......................... ......................... ......................... ......................... qkkeahfplrKYAVKa--------- |
Sc_YDL136W Kl Ca Yl Af Nc Sp Cn Ro_RO3T_13637 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein |
79 | 1 | CI |
YJL187C SWE1 |
469 421 - 447 - 754 592 820 - |
---------kKYAIKaikp--nkyn ---------lKYAIKsvrp--tkhn ......................... gssviltppnRYAVKkmkypfagpk ......................... fssftstp-grhtpevekvfavkki ---------lKYAVKklkvkfsgpk ---------glwavkkargmfdgar ......................... |
Sc_YJL187C Kl_KLLA0B07579g Ca Yl_YALI0F01716g Af Nc_NCUT_03764 Sp_SPCC18B5.03 Cn_cn07077 Ro |
Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate |
80 | 1 | C |
YDR421W ARO80 |
698 684 842 773 758 817 - 749 - |
rqgmlkympvRWVIRiirsiafivk klkmlkympvrwvmrivrsivfmik rfkmlrfmpvrlltrfiraaafivr rmealkyapvRWVVRivhatvflfk pgdhlkhapvrtcfrilsgmifilk pkgylkhapvrtyfriisgamfllk ......................... qmgslrylpsrylinisyaavfalk ......................... |
Sc_YDR421W Kl_KLLA0A01804g Ca_CAL0001342 Yl_YALI0C18645g Af_AFUA_5G13310.t1 Nc_NCUT_00452 Sp Cn_cn08195 Ro |
Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids |
81 | 1 | CI |
YMR162C DNF3 |
1266 1185 1332 619 1163 1100 1280 - - |
rvsdysigqfRFLLKllfvhgryny rssdysiaqfRYLLKllfvhgryny rsadyaiaqfRFLLKlllvngryny rssdfaiaqfsyllklllvhghwny risdysiaqfRFLLKlllvhgrwny risdfsisqfrflqrllfvhgrwny rssdfsigrfKFLIKllfchgrwsy ......................... ......................... |
Sc_YMR162C Kl_KLLA0E01651g Ca_CAL0003528 Yl_YALI0E04169g Af_AFUA_4G10210.t1 Nc_NCUT_03292 Sp_SPAC821.13c Cn Ro |
Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase |
82 | 1 | CI |
YDL140C RPO21 |
403 403 403 408 418 417 409 419 - |
rngpnehpgaKYVIRdsgdridlry rngpnehpgaKYVIResgdridlry rngpnehpgaKYVIRdtgdridlry rngpnehpgaKYVIRdtgeridlry angpnehpgaRYIVRdngeridlrh qngpnehpgaKYVIRsdgsrvdlrh rngpdehpgaKYIIRdtgeridlry nngpatypgaryyvkdtgervdlky ......................... |
Sc_YDL140C Kl_KLLA0F05071g Ca_CAL0000919 Yl_YALI0C16566g Af_AFUA_1G14680.t1 Nc_NCUT_01261 Sp_SPBC28F2.12 Cn_cn05376 Ro |
RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime |
83 | 1 | CI |
YPR145W ASN1 |
451 451 - - - - - 467 - |
--kegr--ieKYILRkafdttgepd --aegk--ieKYILRkafdttdepd ......................... ......................... ......................... ......................... ......................... vdedgrpkmeKYILRkafdcs--pe ......................... |
Sc_YPR145W Kl_KLLA0B10868g Ca Yl Af Nc Sp Cn_cn12090 Ro |
Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway |
84 | 1 | C |
YBL004W UTP20 |
2062 2063 2075 2101 2129 2162 2067 2175 2288 |
qskgrlekqfkfmvdnlqyptesgr qskgrlekqfrfmlnnlqypsqegr qgkgrlekqfkylvsnltypteegr qsrdrlnaefqflihnldypfdsgr qaknrwakqlsflaknldykhqegr qkrnrwekqlkfivanlkyereggr qgktrlskqisfilknleyefapgr qgkgrlksqmtffaqnlqytyeagr qgkgrlkkqmsfiiknlefefesgr |
Sc_YBL004W Kl_KLLA0E17425g Ca_CAL0002346 Yl_YALI0D22440g Af_AFUA_6G08240.t1 Nc_NCUT_02205 Sp_SPBC56F2.04 Cn_cn12221 Ro_RO3T_14432 |
Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA |