DataFormat

MotifLabMotif

Applies to:  Motif and MotifCollection

Description

The MotifLabMotif format is the default format for motifs used by MotifLab, and it is currently the only format that will include information about all the properties related to a motif (and not just the identifier and matrix). The format is basically a direct extension of the INCLUSive Motif Model format but with additional #-fields describing both standard and user-defined motif properties such as the name of the transcription factor (#Short and #Long), the transcription factor class (#Class), binding factors (#Factors), the organisms the TFs are expressed in (#Organisms), motifs for known interacting factors (#Interactions) and alternative motifs models for the same TFs (#Alternatives). A file in MotifLabMotif format must start with a header line reading "#MotifLabMotif" which serves to identify the format.

Example:
#MotifLabMotif (inspired by INCLUSive Motif Model v1.0)
#
#ID = M00002
#Short = V$E47_01
#Long = E47 (E2A immunoglobulin enhancer binding factor)
#W = 15
#Class = 1.2.1.0
#Factors = E47
#Organisms = human (Homo sapiens)
#Interactions = M00001,M00002,M00058,M00065,M00066,M00068,MA0048,MA0081,M00454,MA0092
#Alternatives = M00065,M00066,M00071,M00222,MA0091
#Transfac class = C0010
4.0    4.0    3.0    0.0
2.0    5.0    4.0    0.0
3.0    2.0    4.0    2.0
2.0    0.0    9.0    0.0
0.0    11.0    0.0    0.0
11.0    0.0    0.0    0.0
0.0    0.0    11.0    0.0
1.0    2.0    8.0    0.0
0.0    0.0    0.0    11.0
0.0    0.0    11.0    0.0
0.0    0.0    4.0    7.0
1.0    4.0    3.0    3.0
1.0    6.0    2.0    2.0
1.0    4.0    4.0    2.0
1.0    4.0    2.0    3.0

#ID = M00001
#Short = V$MYOD_01
#Long = MyoD (myoblast determination gene product)
#W = 12
#Class = 1.2.2.0
#Factors = MyoD,MyoD (376 AA),MyoD (275 AA)
#Organisms = chick (Gallus gallus),rat (Rattus norvegicus),human (Homo sapiens)
#Interactions = M00001,M00002,M00004,M00006,M00222,M00223,M00225,M00231,M00232
#Alternatives = M00184
#Transfac class = C0010
1.0    2.0    2.0    0.0
2.0    1.0    2.0    0.0
3.0    0.0    1.0    1.0
0.0    5.0    0.0    0.0
5.0    0.0    0.0    0.0
0.0    0.0    4.0    1.0
0.0    1.0    4.0    0.0
0.0    0.0    0.0    5.0
0.0    0.0    5.0    0.0
0.0    1.0    2.0    2.0
0.0    2.0    0.0    3.0
1.0    0.0    3.0    1.0

Arguments

NameDescription
Include non-standard fields If selected, information about non-standard, user-defined motif properties will also be included.
Include derived fields If selected, motif properties that are derived from other properties, such as GC-content, IC-content and IUPAC consensus string (all derived from the matrix representation), will also be included in the output.
Include color info If selected, information about the current colors used for the motifs in MotifLab will also be included in the output. When a file containing color information is imported into motiflab, the motifs will be assigned their specified colors. If an imported motif file does not contain color information, the motifs will be assigned arbitrary colors.

See Also: INCLUSive_Motif_Model, output